Protein Alignment Myo61F and myo3b

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_073768512.1
• Gene: myo3b / 564573
• ZFINID: ZDB-GENE-070706-2
• Length: 1333
• Species: Danio rerio
• Alignment Length: 851
• Identity: 290/851 - (34%)
• Similarity: 455/851 - (53%)
• Gaps: 112/851 - (13%)

  Fly    20 DFNSQLKMETGLHER---------DRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVL 75
            |..|:.|..   |||         :.....|.|.|| ...||..|.:|:||:|:..||||:|.:|
Zfish   358 DVGSRTKTR---HERINTRKTLIIESCPDDDLVNLE-LLDEETIIAHLQKRYQDLQIYTYVGDIL 418

  Fly    76 ISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEA 140
            |::||::.|.||:....|.|........||||||..|.|::|::...:.||::||||||:||||:
Zfish   419 IALNPFQNLSIYSPQFSKLYHGMKRSTNPPHIFATADAAYQSMVTLCKDQCIIISGESGAGKTES 483

  Fly   141 SKKVLQFIA--ACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAP 203
            :..::|.:.  ..:.|:|    :::|:|:.||::||||||.|..||||||||||::::|...||.
Zfish   484 AHLIVQHLTFLGKANNRT----LREKILQVNPLVEAFGNACTAINDNSSRFGKYLEMKFTPTGAV 544

  Fly   204 IGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGA-DEALLQELRLERALDTYSYLTDGLNGTVT 267
            :|..|..||||||||:.|..||:||||||.:.||. .:..|::.:|..  .|.....|.:||.|.
Zfish   545 MGAKISEYLLEKSRVIKQATGEKNFHIFYYIYAGLYHQDNLRKYKLPN--KTAPRYIDCVNGKVM 607

  Fly   268 R--IND---ADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEG-----NAKVNSR 322
            :  |:.   .:.|..:|....:|.||:||...::.|:|:||:.||:.|.....     .::|.:.
Zfish   608 QDIISSKLYKEQFDAIQDCFRIIGFTEEEVNSVYRILAAILNTGNIEFASASSQHQSDKSEVPNS 672

  Fly   323 DLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRL 387
            :.:..||.||.:.:.||:.|||...:..||:.:......:.|...|||::||:|.|||||:|.|:
Zfish   673 EALDNAAALLSIGSEELQEALTSHCVVTRGETIIRTNTVDKATVVRDAMSKALYGRLFSWIVNRI 737

  Fly   388 NISLQAKETRASRNNVM--GILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRR 450
            |..||......:..:.|  |||||:|||.|:||||||.|||..||::|..|.:.....||.||:.
Zfish   738 NALLQPDTNICAAESGMNVGILDIFGFENFKKNSFEQLCINIANEQIQFYFNQHIFALEQIEYQS 802

  Fly   451 EGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEK 515
            ||::...|||.||:.|.::..:|..|::|:||||...| :.||:|.::|....|...:.::
Zfish   803 EGVDVSLVEYEDNRPILDMFLQKPMGLLSLLDEESRFP-QATDQTLVDKFQDNLRNKYFWI---- 862

  Fly   516 APAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDL----------------KETLSKA 564
             |..::..     |.:.||||:|.|:|:|||:||.|.|..|:                ...|:|.
Zfish   863 -PKRVELC-----FGIQHYAGQVLYNVSGFLEKNRDTLPADIVVVLRTSENRLLQQLFSSPLTKT 921

  Fly   565 GN-------------------GIVRNCFPEKELR-----SLKRPE--------TAITQFRASLNN 597
            ||                   ...||..|:..|:     .::.||        |..:.||.||.:
Zfish   922 GNLATSRARVTAASRSLPPQLNSGRNKSPKYLLKVDTMEMMRHPEETTNMRRQTVASYFRYSLMD 986

  Fly   598 LMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERY 662
            |:..::...|.::|||||||.:.|..||.|.|:.|::|.|::|.:.:||.|:::|...:.|:.||
Zfish   987 LLSKMVVGTPHFVRCIKPNDDRQALRFNKERVMVQLRYTGILETVNIRRQGYSHRILIQEFVNRY 1051

  Fly   663 KSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIA 727
            ..|:   :..::.|.|.|.....:::....|  .:.||.||:|:::    :..|......:..||
Zfish  1052 YYLA---FRAHQMPEGSKENAIIILQKAKLD--YWVVGNTKVFLKY----YHVEQLNLMLREVIA 1107

  Fly   728 AII--QAHWKGLMQRRKYL----KLRAQVIIMQSYCRRKLAQQAAK----KRREAADKIRAFIKG 782
            .::  ||:.||.:..|:|.    |.|...:::||..|..:|:|..|    :|.:||.:|::..:|
Zfish  1108 RVVLMQAYTKGWLGARRYRREREKRRNGAVVIQSAWRGHVARQNLKLIKREREQAAVQIQSVYRG 1172

  Fly   783 FITRND 788
            :..|.|
Zfish  1173 YRVRKD 1178

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	255/717 (36%)
		Myosin_TH1	863..1049	CDD:461801
myo3b	XP_073768512.1	None