Protein Alignment Myo61F and myh9b

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001427874.1
• Gene: myh9b / 561431
• ZFINID: ZDB-GENE-030131-998
• Length: 1960
• Species: Danio rerio
• Alignment Length: 1012
• Identity: 322/1012 - (31%)
• Similarity: 516/1012 - (50%)
• Gaps: 149/1012 - (14%)

  Fly    50 SEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNA 114
            :|.:.:.|||:|:...|||||.|...:.:||||.||||:::.|..|:.|..:||||||:|:||.|
Zfish    91 NEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVDMYKGKKRHEMPPHIYAITDTA 155

  Fly   115 FRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEG----------VKDKLLKSN 169
            :||::::...|.:|.:||||:||||.:|||:|::|..:.:..|.:.          ::.:||::|
Zfish   156 YRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKTKKDQSSSVLSHGELEKQLLQAN 220

  Fly   170 PVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQL 234
            |:|||||||||.:|||||||||::.|.||..|..:|.||..|||||||.:.|...||.||:||.:
Zfish   221 PILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIETYLLEKSRAIRQAKEERTFHMFYYM 285

  Fly   235 LAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIV 299
            |.|..:.|..||.|| ..:.|.:|::| |.|:....|.|.:.:..:|:.::.|::||...:..::
Zfish   286 LTGVGDKLRSELCLE-GYNKYRFLSNG-NVTIPGQQDRDMYVETVEAMRIMGFSEEEHVGLLRVI 348

  Fly   300 ASILHLGNVGFTEVEGNAKVNSRDLVVTAAR----LLGVNASELEAALTHRTIDARGDVVTSPLN 360
            :|:|.|||:.|.:...:.:.:..|  .|||:    |:|:|.::...|:....|....|.|.....
Zfish   349 SSVLQLGNMSFKKERHSDQASMPD--DTAAQKVCHLMGMNVTDFTRAILSPRIKVGRDYVQKAQT 411

  Fly   361 QELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCI 425
            ||.|.:|.:|||||.|:|:|.|||.|:|.:|.  :|:....:.:|||||.|||||:.|||||.||
Zfish   412 QEQAEFAVEALAKATYERMFRWLVMRINKALD--KTKRQGASFIGILDIAGFEIFELNSFEQLCI 474

  Fly   426 NFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEY-FDNKVICNLIEE--KHKGIISILDEECLR 487
            |:.||||||||.......||:||:||||||..::: .|.:...:|||:  ...||:::|||||..
Zfish   475 NYTNEKLQQLFNHTMFILEQEEYQREGIEWSFIDFGLDLQPCIDLIEKPASPPGILALLDEECWF 539

  Fly   488 PGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDE--FRLVHYAGEVTYSVNGFLDKNN 550
            | :.|||:|:||:.|:...|         |...|...|:||  |.::||||:|.|..:.:|.||.
Zfish   540 P-KATDKSFVEKVLQEQGTH---------PKFHKPKKLKDEADFCIIHYAGKVDYKADEWLMKNM 594

  Fly   551 DLLFRDLKETLSKAGNGIVRNCFPE--------------------KELRSLKRPETAITQFRASL 595
            |.|..::...|:::.:..|...:.:                    |..:.:.|  |....::..|
Zfish   595 DPLNDNVATLLNQSTDRFVSELWKDVDRIVGLDKVAGMSELPGAFKTRKGMFR--TVGQLYKEQL 657

  Fly   596 NNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLE 660
            :.||..|....|:::|||.||..:.|...:..|||.|::..|::|.:|:.|.||..|..::.|.:
Zfish   658 SKLMATLRNTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEFRQ 722

  Fly   661 RYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHE 725
            ||:.|:.::.|  ||....|.....:::.|..|...||:|::|:|.|
Zfish   723 RYEILTPNSIP--KGFMDGKQACMLMIRALELDPNLYRIGQSKVFFR------------------ 767

  Fly   726 IAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAP 790
              |.:.||    ::..:.:|:...:|..|::||..:|::|..||::....:|.     |.||.|
Zfish   768 --AGVLAH----LEEERDMKITDVIINFQAWCRGYVARKAFAKRQQQLTAMRV-----IQRNCA- 820

  Fly   791 NGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLH---------RLHLAR 846
                 .::......|.....|..|...:.:.........||.|.:..:..         .:...:
Zfish   821 -----AYLKLRNWQWWRLFTKVKPLLQVSRQEEEMQAKEEELSKVREKQQVAEQQLVEMEVKQQQ 880

  Fly   847 IYRLKLTPQQKRQFELKVLAE-----KVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTF 906
            :...|:..|::.|.|:.:.||     .....||......:..  .|.|:.:|. :|.|...|
Zfish   881 LNAEKMALQEQLQAEMDLCAEADEMRNRLVAKKQELEEILHD--LEARVEEEE-ERANHLQA--- 939

  Fly   907 GSEQLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKI--DFTLTNHNDDL 969
              |:.|.|......::.                  || :....:.:|.|:|:  :..|....:::
Zfish   940 --EKKKMQQNIADLEQQ------------------LD-EEEAARQKLQLEKVTMEAKLKKTEEEV 983

  Fly   970 MVIRIPLD-----LKKDKGDLILIIPRIIEFSTYIID 1001
            ||    ||     |.|:|.   |:..||.||:|.:.:
Zfish   984 MV----LDDQNNKLSKEKK---LMEERIAEFTTNLAE 1013

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	261/693 (38%)
		Myosin_TH1	863..1049	CDD:461801	32/151 (21%)
myh9b	NP_001427874.1	None