Protein Alignment Myo61F and zip

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_523860.2
• Gene: zip / 38001
• FlyBaseID: FBgn0287873
• Length: 2056
• Species: Drosophila melanogaster
• Alignment Length: 1095
• Identity: 334/1095 - (30%)
• Similarity: 522/1095 - (47%)
• Gaps: 221/1095 - (20%)

  Fly    50 SEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNA 114
            :|.:.:.|:|.|:...|||||.|...:.|||||:|||||:..::.|:....:|:|||:||:||:|
  Fly   143 NEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIKRHEVPPHVFAITDSA 207

  Fly   115 FRSLIEENRGQCVLISGESGSGKTEASKKVLQFIA------------------------------ 149
            :|:::.:...|.:|.:||||:||||.:|||:||:|
  Fly   208 YRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYI 272

  Fly   150 -----ACSGNQT--TVEGVK--------------DKLLKSNPVLEAFGNAKTNRNDNSSRFGKYM 193
                 |.:.|||  .|.|:|              .:||::||:|||||||||.:|||||||||::
  Fly   273 KVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFI 337

  Fly   194 DIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALD---TY 255
            .|.||..|...|.||..|||||||.:.|...||.|||||||||||    ..|.|.:..||   :|
  Fly   338 RINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGA----TPEQREKFILDDVKSY 398

  Fly   256 SYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTEVEGNAKVN 320
            ::|::| :..|..::|...|:...:::.::..|.|:...||.||:::|..|::.|.:...|.:..
  Fly   399 AFLSNG-SLPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQAT 462

  Fly   321 SRDLVVT--AARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWL 383
            ..|..|.  .|.|||::.:::..|.....|....|.||....:|...:|.:|:|||.|:|:|.||
  Fly   463 LPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWL 527

  Fly   384 VQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEY 448
            |.|:|.||.  .|:....:.:||||:.|||||:.|||||.|||:.||||||||.......||:||
  Fly   528 VNRINRSLD--RTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEY 590

  Fly   449 RREGIEWIPVEY-FDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVC 512
            :||||||..::: .|.:...:|| :|..||:::|||||..| :.|||||::||....:.|
  Fly   591 QREGIEWKFIDFGLDLQPTIDLI-DKPGGIMALLDEECWFP-KATDKTFVDKLVSAHSMH----- 648

  Fly   513 HEKAPAHIKKIMLRD-----EFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNC 572
                    .|.|..|     :|.:|||||.|.||...:|.||.|.|..::...|..:.:..|.|.
  Fly   649 --------PKFMKTDFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNI 705

  Fly   573 FPEKELRSLKRPETAITQFRA----------------SLNNLMDILMCKEPSYIRCIKPNDLQTA 621
            :.:.|:..:.:.....|||.|                .|..|||.|....|:::|||.||..:.|
  Fly   706 WKDAEIVGMAQQALTDTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRA 770

  Fly   622 NVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQL 686
            ...:..|||.|::..|::|.:|:.|.||..|..::.|.:||:.|:.:..|  ||....|...:::
  Fly   771 GKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIP--KGFMDGKKACEKM 833

  Fly   687 VKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQ-- 749
            ::.|..|...||||::|:|.| ...|...|:....|..::....||..:|.:.||.|.|...|
  Fly   834 IQALELDSNLYRVGQSKIFFR-AGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLN 897

  Fly   750 -VIIMQSYC---------------------------RRKLAQQ--AAKKRREAADKI-------- 776
             :.|:|..|                           ..||.|:  ..|:.||..|.:
  Fly   898 AIRIIQRNCAAYLKLRNWQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYE 962

  Fly   777 RAFIKGFITRNDAPNGFNEEF-----------IANAKRMWLLRLAKELPTKV------------- 817
            |.:.:..:.:.........|.           ...|::..|..:.:||.|::
  Fly   963 RKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGE 1027

  Fly   818 ----------LDKSWPHAPGHCEEASGILHRLHRLHL-ARIYR----LKLTPQQKRQF--ELKVL 865
                      |::....     |||:....:|.::.| |:|.:    |.||..|.::.  |.|:|
  Fly  1028 KKKLELNIQDLEEQLEE-----EEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLL 1087

  Fly   866 AEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSR-- 928
            .|:         |:.:|....|:....:|:.::           :.|:::..::.:...:|.:
  Fly  1088 EER---------ANDLSQTLAEEEEKAKHLAKL-----------KAKHEATISELEERLHKDQQQ 1132

  Fly   929 ----DRFILLSNKAI--YVLDGKTYKQKHRLPLDKIDFTLTNHNDDLMVIRIPLD 977
                ||    |.:.|  .|.|.|....:.|:.:|::...|....::|....:.:|
  Fly  1133 RQESDR----SKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRID 1183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	270/732 (37%)
		Myosin_TH1	863..1049	CDD:461801	21/123 (17%)
zip	NP_523860.2	Myosin_N	79..122	CDD:460670
		MYSc_Myh2_insects_mollusks	145..854	CDD:276876	270/732 (37%)
		Myosin_tail_1	931..2011	CDD:460256	48/282 (17%)