DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Myo61F and didum

DIOPT Version :9

Sequence 1:NP_476934.2 Gene:Myo61F / 38153 FlyBaseID:FBgn0010246 Length:1052 Species:Drosophila melanogaster
Sequence 2:NP_724569.1 Gene:didum / 35680 FlyBaseID:FBgn0261397 Length:1800 Species:Drosophila melanogaster


Alignment Length:1035 Identity:331/1035 - (31%)
Similarity:520/1035 - (50%) Gaps:175/1035 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    38 GVQDFVLLENYQSEEAFIGNLKKRF-QEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFY 101
            |..|...| :|..|...:.||:.|| :..:||||.|.:|:::|||.::|:|....::|||.....
  Fly    71 GQNDLTTL-SYLHEPGVLHNLRVRFCERQIIYTYCGIILVAINPYAEMPLYGPSIIRAYRGHAMG 134

  Fly   102 EMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVKDKLL 166
            ::.|||||:.:.|:..|..||....:::|||||:|||.::|..:::.||..|:::..: |:.|:|
  Fly   135 DLEPHIFALAEEAYTKLERENCNLSIIVSGESGAGKTVSAKYAMRYFAAVGGSESETQ-VERKVL 198

  Fly   167 KSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPI---GGNILNYLLEKSRVVAQMGGERNF 228
            .|:|::||||||||.||||||||||:..:.|..:...:   |..:..|||||||||.|..||||:
  Fly   199 ASSPIMEAFGNAKTTRNDNSSRFGKFTKLLFRNQMGVMFLQGATMHTYLLEKSRVVYQAQGERNY 263

  Fly   229 HIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQR 293
            ||||||.|...:  ..||.|:.. |.:.:|..|....:.|::||:.|.:..||:||:.|:.::..
  Fly   264 HIFYQLCAARSK--YPELVLDHQ-DKFQFLNMGGAPEIERVSDAEQFNETVQAMTVLGFSIQQIA 325

  Fly   294 EIFGIVASILHLGNVGFTEV--EGNAKVNSRD---------LVVTAARLLGVNASELEAALTHRT 347
            :|..|:|.||||||:..::.  ||:.:.:|..         |.:| |.||.|:|.:|...|..|.
  Fly   326 DIVKILAGILHLGNIQVSKKFNEGSEEEDSDSCDIFHNDIHLQIT-ADLLRVSADDLRRWLLMRK 389

  Fly   348 IDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGF 412
            |::..:.|..|.:.|.|..|||||||.:|.:||.::|..||.||.....:.|   .:|:||||||
  Fly   390 IESVNEYVLIPNSIEAAQAARDALAKHIYAKLFQYIVGVLNKSLNNGSKQCS---FIGVLDIYGF 451

  Fly   413 EIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGI 477
            |.|:.|||||||||:.||||||.|.:...|.||:||.:|||.|..::::||:...:|||.: .|:
  Fly   452 ETFEVNSFEQFCINYANEKLQQQFNQHVFKLEQEEYLKEGITWTMIDFYDNQPCIDLIESR-LGV 515

  Fly   478 ISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSV 542
            :.:|||||..| :.:|:::..||..|        |: |.|...|.......|.:.|::..|.|.|
  Fly   516 LDLLDEECRMP-KGSDESWAGKLIGK--------CN-KFPHFEKPRFGTTSFFIKHFSDTVEYDV 570

  Fly   543 NGFLDKNNDLLFRDLKETLSKA----------------------------------------GNG 567
            ||||:||.|.:.::|.:.||::                                        ||.
  Fly   571 NGFLEKNRDTVSKELTQVLSESNMSLAKQVMTLEEIDTLCVDSAKSSTLGGRVVISAGRKQQGND 635

  Fly   568 IVRNCFPEKELRSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQ 632
            ..|...|.|:.|     :|..:||:.||.:|:..|....|.|:|||||||.:.|..:....::.|
  Fly   636 TRRRVVPSKQHR-----KTVGSQFQESLASLISTLHATTPHYVRCIKPNDDKVAFKWETAKIIQQ 695

  Fly   633 VKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKY 697
            ::..|::|.:|:..|||..|..|..|..||:.|   .:.:.......|...:.:|.....||:||
  Fly   696 LRACGVLETVRISAAGFPSRWLYPDFYMRYQLL---VYRSKLDKNDMKLSCRNIVMKWIQDEDKY 757

  Fly   698 RVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLA 762
            |.|.|::|.|..:..| .|......:.:...|:|:..:..:.||::|:::..:..:|.:.|..||
  Fly   758 RFGNTQIFFRAGQVAF-LEQVRANLRKKYITIVQSVVRRFVYRRQFLRIQKVINGIQKHARGYLA 821

  Fly   763 QQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMWL-----LRLAKELPTKVLDKSW 822
            ::..:|.|||    ||   |.|             ::...|.||     |||...:         
  Fly   822 RERTQKMREA----RA---GLI-------------LSKYARGWLCRRRYLRLRHSI--------- 857

  Fly   823 PHAPGHCEEASGILHRLHRLHLAR-IYRLKLTPQQKRQFELKVLAEKVFKGKKNNYASSVSTWFQ 886
               .|....|.|:|.| ::.|..| .||    ..|.::|....||.:.::.::.|..        
  Fly   858 ---SGIQTYARGMLAR-NKFHAMRDHYR----AVQIQRFVRGALARRAYQKRRRNII-------- 906

  Fly   887 EDRIPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFIL-LSNKAIYV-LDGKTYKQ 949
               |.:..|:|   |:|.             .||.|  .|:..:.|. :.||  |: |:.|....
  Fly   907 ---ICQAAIRR---FLAR-------------RKFKR--MKAEAKTISHMENK--YMGLENKIISM 948

  Fly   950 KHRL-PLDKIDFTLTNHNDDLMVIRIPLDLKK--------------DKGDLILIIPRIIE 994
            :.|: .|::.:..|.:...::.|:::.|:|||              ||..||..:.:.:|
  Fly   949 QQRIDELNRDNSNLKHKTSEISVLKMKLELKKTLEAEFKNVKAACQDKDKLIEALNKQLE 1008

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Myo61FNP_476934.2 MYSc 32..720 CDD:214580 266/736 (36%)
MYSc_Myo1 52..707 CDD:276829 258/709 (36%)
Myosin_TH1 863..1035 CDD:283635 31/149 (21%)
didumNP_724569.1 MYSc 65..778 CDD:214580 266/735 (36%)
MYSc_Myo5 84..767 CDD:276831 258/709 (36%)
IQ 900..922 CDD:197470 7/48 (15%)
GBP_C <971..1086 CDD:303769 10/38 (26%)
coiled coil 1049..1068 CDD:293879
coiled coil 1077..1086 CDD:293879
JAKMIP_CC3 <1190..1299 CDD:292653
Myo5_CBD 1424..1792 CDD:271254
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45466259
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR13140
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
32.940

Return to query results.
Submit another query.