Protein Alignment Myo61F and Mhc

DIOPT Version :9

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001162991.1
• Gene: Mhc / 35007
• FlyBaseID: FBgn0264695
• Length: 1962
• Species: Drosophila melanogaster
• Alignment Length: 1061
• Identity: 323/1061 - (30%)
• Similarity: 508/1061 - (47%)
• Gaps: 190/1061 - (17%)

  Fly    57 NLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEE 121
            ||::|:...|||||.|...:::||||:.|:||:...|.||.|...|:||||||::|.|:..::..
  Fly   105 NLRQRYYAKLIYTYSGLFCVAINPYKRYPVYTNRCAKMYRGKRRNEVPPHIFAISDGAYVDMLTN 169

  Fly   122 NRGQCVLISGESGSGKTEASKKVLQFIAACSGNQTTVEGVK------DKLLKSNPVLEAFGNAKT 180
            :..|.:||:||||:||||.:|||:.:.|....::.|.|..|      |:::::||||||||||||
  Fly   170 HVNQSMLITGESGAGKTENTKKVIAYFATVGASKKTDEAAKSKGSLEDQVVQTNPVLEAFGNAKT 234

  Fly   181 NRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQE 245
            .||||||||||::.|.|...|...|.:|..|||||:||::|...||::|||||:::|:...:...
  Fly   235 VRNDNSSRFGKFIRIHFGPTGKLAGADIETYLLEKARVISQQSLERSYHIFYQIMSGSVPGVKDI 299

  Fly   246 LRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGF 310
            ..|...:..|..::.| ..||..|:||:.|....||..::.|||:|:.:::.|.|:::|:|.:.|
  Fly   300 CLLTDNIYDYHIVSQG-KVTVASIDDAEEFSLTDQAFDILGFTKQEKEDVYRITAAVMHMGGMKF 363

  Fly   311 TE--VEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAK 373
            .:  .|..|:.:..:.....::|.|.:.:||...|....|....:.||...|.:....:..||.|
  Fly   364 KQRGREEQAEQDGEEEGGRVSKLFGCDTAELYKNLLKPRIKVGNEFVTQGRNVQQVTNSIGALCK 428

  Fly   374 AVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIE 438
            .|:||||.|||::.|.:|   :|:..|.:.:|:|||.|||||:.|.|||.||||.||||||.|..
  Fly   429 GVFDRLFKWLVKKCNETL---DTQQKRQHFIGVLDIAGFEIFEYNGFEQLCINFTNEKLQQFFNH 490

  Fly   439 LTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQK 503
            .....||:||:||||:|..:::..:.:.|..:.||..||:|||:||.:.| :.||:||.||||.
  Fly   491 HMFVLEQEEYKREGIDWAFIDFGMDLLACIDLIEKPMGILSILEEESMFP-KATDQTFSEKLTN- 553

  Fly   504 LAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGI 568
              .|.......:.|...|.......|.:.||||.|:|::.|:|:||.|.|...:.:...|:.|.:
  Fly   554 --THLGKSAPFQKPKPPKPGQQAAHFAIAHYAGCVSYNITGWLEKNKDPLNDTVVDQFKKSQNKL 616

  Fly   569 VRNCFPE-----------KELRSLKRP--ETAITQFRASLNNLMDILMCKEPSYIRCIKPNDLQT 620
            :...|.:           |..|..|..  .|..:.::..||:||..|...:|.::|||.||:::.
  Fly   617 LIEIFADHAGQSGGGEQAKGGRGKKGGGFATVSSAYKEQLNSLMTTLRSTQPHFVRCIIPNEMKQ 681

  Fly   621 ANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAGVQQ 685
            ..|.:..||:||:...|::|.:|:.|.||..|..|..|..|||.:....   .:|....|...:.
  Fly   682 PGVVDAHLVMHQLTCNGVLEGIRICRKGFPNRMMYPDFKMRYKIMCPKL---LQGVEKDKKATEI 743

  Fly   686 LVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQRRKYLKLRAQV 750
            ::|.:...|::||:|.||:|.| ...|...|:...|:..:|.:.:||..:|.:.|:.:.||:.|.
  Fly   744 IIKFIDLPEDQYRLGNTKVFFR-AGVLGQMEEFRDERLGKIMSWMQAWARGYLSRKGFKKLQEQR 807

  Fly   751 I---IMQSYCRRKL-----------------------------AQQAAKKRRE--AAD-KIR--- 777
            :   ::|...|:.|                             .::.|||..|  ||: |:|
  Fly   808 VALKVVQRNLRKYLQLRTWPWYKLWQKVKPLLNVSRIEDEIARLEEKAKKAEELHAAEVKVRKEL 872

  Fly   778 ------------AFIKGFITRNDAPNGFNEEFIANAKRMWLLRLAKELPTKVLDKSWPHAPGHCE 830
                        |.:........|...:.|.   |||   |.....:|..::.|
  Fly   873 EALNAKLLAEKTALLDSLSGEKGALQDYQER---NAK---LTAQKNDLENQLRD----------- 920

  Fly   831 EASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVFKGKKNNYAS---SVSTWFQEDRIPK 892
                |..||.:...||          .:.|:.|..|::...|.|.:...   :|.. .::|:..|
  Fly   921 ----IQERLTQEEDAR----------NQLFQQKKKADQEISGLKKDIEDLELNVQK-AEQDKATK 970

  Fly   893 EH-IQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKT---------- 946
            :| |:.:||.:|                       .:|..|...||. ..:.|:|
  Fly   971 DHQIRNLNDEIA-----------------------HQDELINKLNKE-KKMQGETNQKTGEELQA 1011

  Fly   947 ----------YKQKHRLPLDKIDFTLTNHNDDLMVIRIPLDLKKDK----GDLILIIPRIIEFST 997
                      .|.|....||:::.:|....      ::..|::|.|    |||.|
  Fly  1012 AEDKINHLNKVKAKLEQTLDELEDSLEREK------KVRGDVEKSKRKVEGDLKL---------- 1060

  Fly   998 YIIDTVGTASIVSIVDRNSLE 1018
                   |...|:.::||..|
  Fly  1061 -------TQEAVADLERNKKE 1074

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	253/683 (37%)
		MYSc_Myo1	52..707	CDD:276829	250/670 (37%)
		Myosin_TH1	863..1035	CDD:283635	35/184 (19%)
Mhc	NP_001162991.1	Myosin_N	36..73	CDD:280832
		MYSc	81..777	CDD:214580	253/683 (37%)
		MYSc_Myh1_insects_crustaceans	100..765	CDD:276874	250/670 (37%)
		Myosin_tail_1	842..1897	CDD:279860	58/312 (19%)
		V_Alix_like	1557..1877	CDD:187408
		ATP-synt_B	<1671..1771	CDD:304375
		TMPIT	1739..>1825	CDD:285135

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466283
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840