Protein Alignment Myo61F and Myo31DF

DIOPT Version :9

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001188784.1
• Gene: Myo31DF / 34445
• FlyBaseID: FBgn0086347
• Length: 1011
• Species: Drosophila melanogaster
• Alignment Length: 1068
• Identity: 421/1068 - (39%)
• Similarity: 622/1068 - (58%)
• Gaps: 129/1068 - (12%)

  Fly    37 AGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFY 101
            |||||||||:.. |.|.|:.||:||||...||||||:|.:|:|||:|:.||..:.::.|:.:..:
  Fly     7 AGVQDFVLLDQV-SMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELF 70

  Fly   102 EMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAACSG--NQTTVEGVKDK 164
            |..||:||:.|:|:|.|.:..:..|:|||||||:|||||||.::::|||.:.  .|..:|.||:.
  Fly    71 ENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNV 135

  Fly   165 LLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFH 229
            |::||.:||.|||||||||||||||||||||:||:|..|:||.|.||||||||||.|..||||||
  Fly   136 LIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFH 200

  Fly   230 IFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQALTVIDFTKEEQRE 294
            .|||||.||::..|::..|::....|.||..|....:|..:|   :|....|...:.|:.:|.:.
  Fly   201 SFYQLLRGANDNELRQYELQKETGKYHYLNQGSMDILTEKSD---YKGTCNAFKTLGFSTDEVQT 262

  Fly   295 IFGIVASILHLGNVGFTEVEGNAKVNSRDLVVTAARLLGVNASELEAALTHRTIDARGDVVTSPL 359
            |:..:|::||||||.|..:|....::::..:.:.|:||.|..:||..|||.|.|.|.|:|:....
  Fly   263 IWRTIAAVLHLGNVEFQTIEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQKDH 327

  Fly   360 NQELAIYARDALAKAVYDRLFSWLVQRLN--ISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQ 422
            |...|.|.:||||||:|||||:|::.|:|  |..:..:|:|..|:|:|:|||||||||..|||||
  Fly   328 NATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQARFNSVIGVLDIYGFEIFDSNSFEQ 392

  Fly   423 FCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHKGIISILDEECLR 487
            ||||:||||||||||||.||.||:||:||||||..:|||:||:||:|:|:.|||||:|:||.||.
  Fly   393 FCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEACLS 457

  Fly   488 PGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTYSVNGFLDKNNDL 552
            .|:.||.|.|..:.:.|::|.||...:..|.. |::..|::||:.||||:|.|::|||::||.|.
  Fly   458 VGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTD-KELKHREDFRITHYAGDVIYNINGFIEKNKDT 521

  Fly   553 LFRDLKETLSKAGNGIVRNCFPE--KEL-RSLKRPETAITQFRASLNNLMDILMCKEPSYIRCIK 614
            |::|.|..|..:.:..:...:||  ::: ::.|||.||.|.|:.|:.:|:..|:.|||.|:||||
  Fly   522 LYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIK 586

  Fly   615 PNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGP 679
            ||||:::.||::|.|.|||:||||:||||||||||.:|:.|:.||.|||.:|:.||||::. |..
  Fly   587 PNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRA-GSD 650

  Fly   680 KAGVQQLVKDLGWDEEKY----RVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWKGLMQR 740
            :.||:.|:     :|:|:    :.|.||:|||.|||||..|....|....|..::|...:|.:.|
  Fly   651 RDGVRVLI-----EEKKFAQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVR 710

  Fly   741 RKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIANAKRMW 805
            |.:.|::|.:.|:::|               .|.|:|::::....|
  Fly   711 RNFKKMKAAITIVRAY---------------KAYKLRSYVQELANR------------------- 741

  Fly   806 LLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVLAEKVF 870
             ||.||::........||..|....:....|||:.....|.:...|....:..|..|:::|....
  Fly   742 -LRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATAL 805

  Fly   871 KGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVAS-------------------------TFGSEQ 910
            .|:: .|......|             |.|::|:                         ||  :|
  Fly   806 AGRR-PYWGQARRW-------------VGDYLANSQENSGYEAYNGSIKNIRNHPADGETF--QQ 854

  Fly   911 LKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKI----DFTLTNHNDDLMV 971
            :.:.||..||: |..|..:|..::|:..|:.|||...|.|......||    ..:::...|.|:|
  Fly   855 VLFSSFVKKFN-HFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIV 918

  Fly   972 IRIPLDLKKDKGDLILIIPRIIEFSTYIIDTVGTASIVSIVDR-------NSLEHNV-------V 1022
            ..    ..|:| ||:..:..  |::....|.:|  .:|.||.:       ..|..||       :
  Fly   919 FH----SSKNK-DLVFSLES--EYTPLKEDRIG--EVVGIVCKKYHDLTGTELRVNVTTNISCRL 974

  Fly  1023 KGKGGVIDIQTGAE---PGVVRDKGHLV 1047
            .||..:|.::..:.   |.....:|:::
  Fly   975 DGKARIITVEAASNVEVPNFRPKEGNII 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	346/693 (50%)
		MYSc_Myo1	52..707	CDD:276829	328/665 (49%)
		Myosin_TH1	863..1035	CDD:283635	45/214 (21%)
Myo31DF	NP_001188784.1	MYSc	6..690	CDD:214580	346/693 (50%)
		MYSc_Myo1	21..677	CDD:276829	328/665 (49%)
		Myosin_TH1	801..983	CDD:283635	45/207 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466276
Domainoid	1	1.000	519	1.000	Domainoid score	I47
eggNOG	1	0.900	-	-		E2759_KOG0164
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	555	1.000	Inparanoid score	I192
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D122881at2759
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	1	1.000	-	-		mtm9169
orthoMCL	1	0.900	-	-		OOG6_100187
Panther	1	1.100	-	-	P	PTHR13140
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	10	9.800