Protein Alignment Myo61F and dachs

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_001188730.1
• Gene: dachs / 34179
• FlyBaseID: FBgn0262029
• Length: 1426
• Species: Drosophila melanogaster
• Alignment Length: 914
• Identity: 247/914 - (27%)
• Similarity: 395/914 - (43%)
• Gaps: 196/914 - (21%)

  Fly    23 SQLKMETGLHERDRAG------VQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPY 81
            ||.||:    ::.:.|      :||.:.|....:|.|.:..|:.||.|...:|.:|.:|:|:|||
  Fly   457 SQQKMQ----QQQQQGNSSPKDMQDLIHLSGPLTEHAVMRTLQARFNERRYFTNVGPILLSINPY 517

  Fly    82 KQL--PIYTDDHVKAYRNKHFYEMP--PHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASK 142
            ..:  |: |....:|        ||  |.:..:...|.|...|....|.:::||.||:|||..:.
  Fly   518 LDVGNPL-TLTSTRA--------MPLAPQLQKIVQEAVRQQSETGYPQAIILSGTSGAGKTANAM 573

  Fly   143 KVLQFIAACSGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGN 207
            .:|:.:.|.:|.....:..| .|..:..||.:.|:|||..|..|||.|:::::|.. .||.....
  Fly   574 LMLRQLFAIAGGGPETDAFK-HLAAAFTVLRSLGSAKTTTNSESSRIGQFIEVQVT-DGALYRTK 636

  Fly   208 ILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYS-----YLTDGLNGTVT 267
            |..|.|:::||:..:..|:|:|||||||||    |.:|.|.:..||.||     ||...:.  ..
  Fly   637 IHCYFLDQTRVIRPLPKEKNYHIFYQLLAG----LSREERQKLHLDGYSPANLRYLRGDIG--QN 695

  Fly   268 RINDADSFKQVQQALTV--IDFTKEEQREIFGIVASILHLGNVGF-------TEVEGNAKVNSRD 323
            ...||..|:..:..|.:  |.|.     ::..::|::|.||||.|       .:|:|..::||
  Fly   696 EQEDAARFQAWKTCLGILGIPFL-----DVVRVLAAVLLLGNVQFIDGGGLEVDVKGETELNS-- 753

  Fly   324 LVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLN 388
                .|.||||..:.|...||.||.:.||.:|.|......|...||.||||:|.|..:.:|:|.|
  Fly   754 ----VASLLGVPPAALFRGLTTRTHNVRGQLVKSVCGDGDANMTRDCLAKALYCRTVATIVRRAN 814

  Fly   389 -----------ISLQAKE------------------------TRASRNNV---------MGILDI 409
                       :|..:.|                        :.|:.||.         :||||:
  Fly   815 SLKRLGSTLGTLSSDSNESVHNQADVASQHASTIGGGNAGSKSMAALNNAVRHATSDGFIGILDM 879

  Fly   410 YGFEIFQKNS-FEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEW-IPVEYFDNKVICNLIEE 472
            :|||....:: .|..|||.|.|.:|..:.....||..:..|.|||.. ..|:|.||....:||..
  Fly   880 FGFEEPSPHAHLEHLCINLCAETMQHFYNTHIFKSSVESCRDEGIVCDTEVDYVDNVPCIDLISS 944

  Fly   473 KHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPA---HIKKIMLRDEFRLVHY 534
            ...|::|:||.||...|  |.::::.||.   .||......|..|.   |..::     |.:.|:
  Fly   945 LRTGLLSMLDAECSVRG--TAESYVTKLK---VQHRSSTRLETKPTAEPHDPRM-----FLIRHF 999

  Fly   535 AGEVTYSVNGFLDKNNDLLFRDL-----KETLS-------------------KAGNGIVRNCFP- 574
            ||.|.|....|||.|.|::..||     |.|.:                   :|..|:.....|
  Fly  1000 AGRVEYDTTDFLDTNRDVVPDDLVGVFYKHTCNFGFATHLFGSELKALYAQQQAPRGLSFRISPT 1064

  Fly   575 -EKELRSLKRPETAITQ-FRASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLG 637
             ..:|.:...|.:.:|| |...|:||:..|:...|.::|||:.|..:.|..|:...|:.|::.|.
  Fly  1065 SHSDLLNGDEPVSTLTQDFHTRLDNLLRTLVHARPHFVRCIRSNGTEAARSFDRATVVRQIRSLQ 1129

  Fly   638 LMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGP----KAGVQQLVKD----LGWDE 694
            ::|.:.:..:||.:|..::.|..||:.|:            |    :....:.::|    |.:..
  Fly  1130 VLETVNLMASGFPHRMRFKQFNARYRMLA------------PFRLLRRSEDKALEDCQLILKYAM 1182

  Fly   695 EKYRVGETKLFIRW---PRTLFDTEDAYQ-------EKKHEIAAIIQAHWKGLMQRRKYLKLRAQ 749
            |:..|.:..:.:.|   .|.:|.:|...|       |.:|:.|.::||.|:|.
  Fly  1183 EQPPVLDGSVTLAWAPGKRHVFLSEGIRQHLEHLRTEIRHKSATLMQATWRGW------------ 1235

  Fly   750 VIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRN-DAPNGFNEEFIANAKRMWLLRLAKEL 813
                  :.|:|:....||:     .||....:..:..| ..||...:...|::....|..:|...
  Fly  1236 ------WWRKKMGNGGAKR-----SKIPGLQQAPLPNNKTTPNSAAQNKAASSTMAALAAVAAAA 1289

  Fly   814 PTKV 817
            |..|
  Fly  1290 PISV 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	212/756 (28%)
		Myosin_TH1	863..1049	CDD:461801
dachs	NP_001188730.1	MYSc_Myo20	488..1206	CDD:276847	215/767 (28%)
		IQCD	1219..1250	CDD:467745	11/53 (21%)