Protein Alignment Myo61F and nmy-1

DIOPT Version :9

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_508504.2
• Gene: nmy-1 / 180581
• WormBaseID: WBGene00003776
• Length: 1963
• Species: Caenorhabditis elegans
• Alignment Length: 1087
• Identity: 340/1087 - (31%)
• Similarity: 530/1087 - (48%)
• Gaps: 188/1087 - (17%)

  Fly    17 DYIDFNSQLKMETGLHERD---RAGVQDFVLLEN-----YQSEEAFIGNLKKRFQEDLIYTYIGQ 73
            :.:|.:.|:.:     .||   :|....|..:|:     |.:|.:.:.|||.|:...|||||.|.
 Worm    54 ELVDTSRQVTI-----SRDDVQKANPPKFDKIEDMSELTYLNEASVLHNLKDRYYSSLIYTYSGL 113

  Fly    74 VLISVNPYKQLPIYTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKT 138
            ..:.:||||:||||::|.::.::.|..:||||||||:.|.|:||:::|...|.:|.:||||:|||
 Worm   114 FCVVINPYKKLPIYSEDLIEEFKGKKRHEMPPHIFAIADTAYRSMLQEREDQSILCTGESGAGKT 178

  Fly   139 EASKKVLQFIAACSG-------NQTTVEGVKDK-------------LLKSNPVLEAFGNAKTNRN 183
            |.:|||:|::|..:|       |....:.:..|             ||::||:||||||:||.:|
 Worm   179 ENTKKVIQYLAHVAGATRNKSLNAAAQQNIVQKPDVRNPIGELEHQLLQANPILEAFGNSKTVKN 243

  Fly   184 DNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSRVVAQMGGERNFHIFYQLLAGADEALLQELRL 248
            ||||||||::.|.||..|...|.||..||||||||:.|...||:||||||:|.|.......|..|
 Worm   244 DNSSRFGKFIRINFDMSGYISGANIEFYLLEKSRVLRQAQDERSFHIFYQILRGCSAKEKSEYLL 308

  Fly   249 ERALDTYSYLTD-GLNGTVTRINDADSFKQVQQALTVIDFTKEEQREIFGIVASILHLGNVGFTE 312
            | .:|.|.:|.: |:  |:..::|...|.....::.::.|..:|...|..:|:::|.|||:.||:
 Worm   309 E-GVDNYRFLVNRGI--TLPNVDDVQEFHSTINSMRIMGFADDEISSIMRVVSAVLLLGNLEFTQ 370

  Fly   313 VEGNAKVNSRD--LVVTAARLLGVNASELEAALTHRTIDARGDVVTSPLNQELAIYARDALAKAV 375
            .:.:.:...:|  ::.....|||:...||:.|.....|....:.|....|||.|.:|.:|:|||.
 Worm   371 EKKSDQAMLQDDRVIQKVCHLLGLPVIELQKAFLRPRIKVGREFVNKAQNQEQAEFAVEAIAKAS 435

  Fly   376 YDRLFSWLVQRLNISLQAKETRASRNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELT 440
            |:|||.|||.|:|.||.  .|.....:.:|||||.|||||..|||||.|||:.||||||||....
 Worm   436 YERLFKWLVTRINKSLD--RTHRQGASFIGILDIAGFEIFDINSFEQICINYTNEKLQQLFNNTM 498

  Fly   441 LKSEQDEYRREGIEWIPVEY-FDNKVICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKL 504
            ...||:||:||||||..::: .|.:...:|| ||..|::::||||||.| :..||:|:||| ||
 Worm   499 FILEQEEYQREGIEWDFIDFGLDLQPTIDLI-EKPMGVLALLDEECLFP-KANDKSFVEKL-QK- 559

  Fly   505 AQHHHYVCHEKAPAHIKKIM-LRDEFRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGI 568
                   .|.|.|..|...| .:..|.:|||||.|.||.:.:|.||.|.|..::...:..:.:..
 Worm   560 -------THNKHPKFIVPDMRSKSHFAVVHYAGRVDYSADQWLMKNMDPLNENVVGLMQNSTDPF 617

  Fly   569 VRNCFPEKE---------------LRSLKRPETAITQF-RASLNNLMDILMCKEPSYIRCIKPND 617
            |...:.:.|               :||.|.....::|. :..|..||..|....|.::|||.||.
 Worm   618 VAGIWKDAEFAGICAAEMNETAFGMRSRKGMFRTVSQLHKEQLTKLMTTLRNTSPHFVRCIIPNH 682

  Fly   618 LQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTWPNYKGPGGPKAG 682
            .:.:...|..|||.|::..|::|.:|:.|.||..|..::.|..||:.|:....|.....|  |..
 Worm   683 EKKSGKINSNLVLEQLRCNGVLEGIRICRQGFPNRVPFQEFRHRYEILTPDVIPKNFIDG--KES 745

  Fly   683 VQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAII---QAHWKGLMQRRKYL 744
            |::::..|..|...||:|::|:|.| ...|...|   :|:..::.|:|   ||..:|.:.||.|.
 Worm   746 VRKMITALDIDTNLYRIGQSKVFFR-TGVLAHLE---EERDLKLTALIMNFQAQCRGFLSRRLYT 806

  Fly   745 KLRAQVIIMQSYCRRKLAQQAAKKRR--EAADKIRAFIKGFITR-NDAPNGFNEEFIANAKRMWL 806
            :.:.|...::...|..||....:..:  ....|::..::  :|| :|.....::|..|..:|  |
 Worm   807 RRQQQSSAIRIIQRNGLAYLKLRNWQWWRLFTKVKPLLQ--VTRTDDEIRAKDDELRATKER--L 867

  Fly   807 LRLAKE------------LPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQ 859
            |::..:            :...|:.:.......:..|...|..||                |.|.
 Worm   868 LKMEHDFRENEKKLDQVIVERAVIQEQLQQESENSAELDDIRGRL----------------QTRN 916

  Fly   860 FELKV--------LAEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSEQLKYQSF 916
            .||:.        |:|:..:.:|||          ::|  ::.::.|.|.      .|||:.:.
 Worm   917 QELEYIVNDMRDRLSEEEQQNEKNN----------DER--RKQMETVRDL------EEQLEQEE- 962

  Fly   917 CTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDK--IDFTLTNHNDDLMVIRIPLDLK 979
                                           :.:.:|.|||  :|..|.|..:.|:.:
 Worm   963 -------------------------------QARQKLLLDKTNVDQRLRNLEERLVEL------- 989

  Fly   980 KDKGDLILIIPRIIEFSTYIIDTVGTASIVSIVDRNSLEHNVVKGKG 1026
            :|..|.:|...|::|.....:.|       .::|......:.||.||
 Worm   990 QDAYDKLLKEKRLLEEKVEGLTT-------QLLDHEERAKHGVKAKG 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	277/736 (38%)
		MYSc_Myo1	52..707	CDD:276829	267/695 (38%)
		Myosin_TH1	863..1035	CDD:283635	30/174 (17%)
nmy-1	NP_508504.2	Myosin_N	27..65	CDD:280832	2/15 (13%)
		Myosin_head	80..770	CDD:278492	270/707 (38%)
		MYSc_class_II	92..770	CDD:276951	267/695 (38%)
		Myosin_tail_1	847..1919	CDD:279860	47/265 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910