Protein Alignment Myo61F and Myo10

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: NP_062345.2
• Gene: Myo10 / 17909
• MGIID: 107716
• Length: 2062
• Species: Mus musculus
• Alignment Length: 67
• Identity: 17/67 - (25%)
• Similarity: 27/67 - (40%)
• Gaps: 13/67 - (19%)

  Fly    23 VAKVYCFLHV-----TTNYLGFMAYAYGPSM-IPTLHPSGNMLLAERISKRYQKPSRGDIVVIRS 81
            ::::...:|:     ..|.||......||.| |......||:       ..|.:..|||.||.:|
Mouse   856 MSELKILIHIGHHLNVVNLLGACTKRGGPLMIIVEFCKYGNL-------SNYLRSKRGDFVVYKS 913

  Fly    82 PE 83
            .:
Mouse   914 QD 915

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	9/32 (28%)
		Myosin_TH1	863..1049	CDD:461801
Myo10	NP_062345.2	SH3_19	7..58	CDD:465815
		MYSc_Myo10	77..727	CDD:276840
		Actin-binding. /evidence=ECO:0000255|PROSITE-ProRule:PRU00782	619..641
		DUF5401	<727..982	CDD:375164	17/67 (25%)
		SAH. /evidence=ECO:0000250|UniProtKB:Q9HD67	814..882		4/25 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	822..844
		TPH	<840..946	CDD:464007	17/67 (25%)
		MYO10_CC	882..932	CDD:465249	13/41 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	963..1047
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1062..1089
		PH-like	1185..>1227	CDD:473070
		PH2_MyoX	1219..1320	CDD:270108
		PH3_MyoX-like	1385..1510	CDD:270109
		MyTH4	1553..1699	CDD:214535
		FERM_F1_Myosin-X	1701..1796	CDD:340726
		B41	1708..1962	CDD:214604
		FERM_C_MyoX	1958..2046	CDD:270023