Protein Alignment Myo61F and Myo95E

DIOPT Version :10

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_061502440.1
• Gene: Myo95E / 1274548
• VectorBaseID: AGAMI1_000001
• Length: 1256
• Species: Anopheles gambiae
• Alignment Length: 1260
• Identity: 367/1260 - (29%)
• Similarity: 572/1260 - (45%)
• Gaps: 309/1260 - (24%)

  Fly    38 GVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPIYTDDHVKAYRNKHFYE 102
            |..|.|||||. |||:||.||.:|::.||||||||..|:::||||.|.||..|.|:.|..|..::
Mosquito    20 GSWDSVLLENL-SEESFINNLHQRYKRDLIYTYIGTFLVALNPYKPLQIYNPDQVRKYATKSLFQ 83

  Fly   103 MPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFI------------------- 148
            :||||||:.::|.:.|:..|..||::::||.||||||:|..::.|:
Mosquito    84 LPPHIFALANSAHQFLLNYNEDQCIIMAGECGSGKTESSHMIVHFLTQLSEMRRSRAPIFSLRGS 148

  Fly   149 -----------------------AACSG------------------------------------- 153
                                   ||.||
Mosquito   149 NPNSRQSTPKHSTISRVGSSFESAAPSGGRLDSIMKYNSSRQQKCSHEKTVEFDLISHHKSTENL 213

  Fly   154 ---------------------NQT---TVEG---------------------------------- 160
                                 ||:   :.||
Mosquito   214 PAMVNYGFMPVATMPKCLKHSNQSISRSTEGNEFPTKSTLKSATTMGSCPKHNCTSSHAELNRMC 278

  Fly   161 ----------------------------------------------------------------- 160
                                                                             
Mosquito   279 GGASPSPSLQKRSNLMRCCHQNSNNSTRSIHKSSSSIALTHDHGTTSPSTFHRRQILKSISKEVY 343

  Fly   161 --------VKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKSR 217
                    :::::.::...|||.|||.|.:|.|||||||:.||:||:||.|:||::..|:|||||
Mosquito   344 IRDLELQKMRERVAQAEIFLEAMGNAVTVKNINSSRFGKFFDIEFDYKGDPVGGHLTLYMLEKSR 408

  Fly   218 VVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQAL 282
            |..:..||||||||||||:|||..||:.|:|:|.:|.|..    |..|....:|..:|...:::|
Mosquito   409 VTTRASGERNFHIFYQLLSGADIQLLKSLKLQRNIDKYEL----LKNTFANEDDRTNFTFTKRSL 469

  Fly   283 TVIDFTKEEQREIFGIVASILHLGNVGF---TEVEGN--AKVNSRDLVVTAARLLGVNASELEAA 342
            .::.|.::|...||.|:|.:|.|||:.|   |.::|:  .::::...:...|:||     :|:..
Mosquito   470 EILGFGQDEIFSIFTILAVVLKLGNLTFIPTTNIDGSEGCEISNEYELDEIAQLL-----QLDNQ 529

  Fly   343 LTHRTIDARGD--VVTSPLNQEL-AIYA---RDALAKAVYDRLFSWLVQRLNISLQAKE--TRAS 399
            :....:...||  ....|...|: |.||   :..|.:.:|.|||:|:|.|:|.:|:.|.  |..|
Mosquito   530 MLFNCLTRLGDNWAQLEPDGTEIDASYASRIKFTLCRTLYGRLFTWIVSRVNDALKLKTSGTVGS 594

  Fly   400 RNNVMGILDIYGFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNK 464
            |...:|:||.||||..:||:|:||.||:|||:|||.||:..||.:||.|..||::||.:::|||.
Mosquito   595 RGKTIGLLDFYGFEALEKNTFDQFAINYCNERLQQHFIKSVLKHQQDLYVNEGLDWIRIDFFDNA 659

  Fly   465 VICNLIEEKHKGIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKA-PAHIKKIMLRDE 528
            .||.||::...||:.:|||    |....|...|.:|.|..|.|.:::..:.: |::.
Mosquito   660 PICELIDKPCFGILHLLDE----PQVVNDGLLLTRLHQCCAGHTNFLARDASLPSNC-------- 712

  Fly   529 FRLVHYAGEVTYSVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPE--KELRSLKRPETAITQF 591
            |::.|:.|.|.|:.|||::||.|||.|.:...|.::...|....|||  .:..|.::|.:.....
Mosquito   713 FQVRHFEGPVVYTTNGFIEKNLDLLPRHISSCLFQSDLLIASCLFPEGNPKRHSNRKPSSLSNNL 777

  Fly   592 RASLNNLMDILMCKEPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYE 656
            |.||..|:.:|..:...||.|||||:|:.|.:|...||.|||:||.||..:.:.|.|..:...:.
Mosquito   778 RTSLQTLLKLLEQRSNHYIFCIKPNELKQAKMFELGLVQHQVRYLCLMPLINLWRNGHCFNMVHS 842

  Fly   657 LFLERYKSLSKSTWPNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQE 721
            .||.|||.|.:.|||::.|.  ...||..:::.:.....::.:|..|:|||.|||:::.::..:.
Mosquito   843 RFLARYKLLCQYTWPHFTGT--IVDGVALIIRSVPLPGAEFTIGRKKVFIRSPRTVYELDEFRKV 905

  Fly   722 KKHEIAAIIQAHWKGLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIR--AFIKGFI 784
            :.:|:|.:||..::...:|:::|.||...:|:.||.|       ..:.||   |||  .|.|..:
Mosquito   906 RLNELAILIQKTYRCYTKRKRFLTLRHSQLIIASYWR-------TWRERE---KIRLVEFRKQAL 960

  Fly   785 TRNDAPNGFNEEFIANAKRMWLLRLAKELP---TKVLDKSWPHAPGHCEEASGILHRLHRLHLAR 846
            ........|   |:....|.:||.|...||   ...:...||.||....|.|.:|..:  .|..|
Mosquito   961 WAVQVIGRF---FVLLKTREFLLTLLLRLPHDNMSPICHEWPSAPTFLAETSQLLRTI--FHRWR 1020

  Fly   847 IYRLKLT---PQQKRQFELKVLAEKVFKGKKNNYASSVSTWFQEDRIP-KEHIQRVNDFVASTFG 907
            .|:.:.:   |.:.|..| ||.|..:||.:|.:|..||:..|..|.|. :::||...  |:....
Mosquito  1021 CYKYRKSFDQPARNRMRE-KVTASIIFKDRKVSYPRSVAHPFHGDYIRLRQNIQWKR--VSCEHN 1082

  Fly   908 SEQLKYQSFCTKFDRHGYKSRDRFILLSNKAIYVLDGKTYKQKHRLPLDKI-DFTLTNHNDDLMV 971
            .:.:.:.....|..|...|.....:::|..::.:||.||.:.|:|:|..:| ..:|:.:.||:.|
Mosquito  1083 DQYVVFADIINKIARSSGKFIPILLVISTNSMLLLDQKTMQIKYRIPASEIYRMSLSPYFDDIAV 1147

  Fly   972 IRIPLD----------------------LKKDKGDLILIIPRIIEFST--YIIDTVGTASIVSIV 1012
            |.|..|                      :.|.|||.:......||..|  :::....||....:.
Mosquito  1148 IHIRADNYCSSNMSDRSESPTGCLFQSEIGKKKGDFVFQTAHSIEIVTKLFLVIQNATAKSPEVT 1212

  Fly  1013 DRNSLEHN------VVKGK-GGVID 1030
            .....|.|      :...| ||::|
Mosquito  1213 ISTDFEANFGGQTVIFTFKCGGLVD 1237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc_Myo1	52..707	CDD:276829	264/880 (30%)
		Myosin_TH1	863..1049	CDD:461801	49/201 (24%)
Myo95E	XP_061502440.1	None