Protein Alignment Myo61F and myo1h

DIOPT Version :9

• Sequence 1: NP_476934.2
• Gene: Myo61F / 38153
• FlyBaseID: FBgn0010246
• Length: 1052
• Species: Drosophila melanogaster
• Sequence 2: XP_017945451.1
• Gene: myo1h / 100492763
• XenbaseID: XB-GENE-963784
• Length: 1036
• Species: Xenopus tropicalis
• Alignment Length: 1035
• Identity: 520/1035 - (50%)
• Similarity: 705/1035 - (68%)
• Gaps: 24/1035 - (2%)

  Fly    22 NSQLKMETGLHERDRAGVQDFVLLENYQSEEAFIGNLKKRFQEDLIYTYIGQVLISVNPYKQLPI 86
            |.::.||..|..||:.||||||||:::.||.||:.||:|||||:|||||||.:|:|||||::|.:
 Frog    11 NGRMHMEGSLSARDKVGVQDFVLLDSHTSEAAFMDNLRKRFQENLIYTYIGTMLVSVNPYQELQL 75

  Fly    87 YTDDHVKAYRNKHFYEMPPHIFAVTDNAFRSLIEENRGQCVLISGESGSGKTEASKKVLQFIAAC 151
            ||...::.|:..:|.|:||||:||.|||:|.:..|.....:||||||||||||.|||:||::|..
 Frog    76 YTQRQMELYQGVNFIELPPHIYAVADNAYRVMCTERNNHFILISGESGSGKTETSKKILQYLAMT 140

  Fly   152 SGNQTTVEGVKDKLLKSNPVLEAFGNAKTNRNDNSSRFGKYMDIQFDFKGAPIGGNILNYLLEKS 216
            ......::.::|:||.|||||||||||||.|||||||||||||:|||:||||.||:||:||:|||
 Frog   141 CPVTEKLQTIRDRLLLSNPVLEAFGNAKTIRNDNSSRFGKYMDVQFDYKGAPAGGHILSYLIEKS 205

  Fly   217 RVVAQMGGERNFHIFYQLLAGADEALLQELRLERALDTYSYLTDGLNGTVTRINDADSFKQVQQA 281
            |||.|..||||||||||||.|.::.|::.|.|||....||||..|....|:.|.|..::|.|::|
 Frog   206 RVVHQNPGERNFHIFYQLLEGGEDHLIRWLGLERNPQMYSYLIQGECAKVSSICDKTNWKLVRRA 270

  Fly   282 LTVIDFTKEEQREIFGIVASILHLGNVGFTE-VEGNAKVNSRDLVVTAARLLGVNASELEAALTH 345
            .|:|:||:.:...:||||||:|||||:.:.| ..|:|.:.:...:...::||||..|.|:.|||:
 Frog   271 FTIIEFTEADIEHLFGIVASVLHLGNIKYEEDTHGHAIIRNGSQMQWISKLLGVPVSILQEALTN 335

  Fly   346 RTIDARGDVVTSPLNQELAIYARDALAKAVYDRLFSWLVQRLNISLQAKETRASRNNVMGILDIY 410
            :.|:||.:.|.||||.|||.|||||||||:|.|.|:|||.::|.||..|:  ..:..|:|:||||
 Frog   336 KKIEARSEEVLSPLNLELAYYARDALAKAIYGRSFNWLVNKINSSLANKD--PPKKTVIGLLDIY 398

  Fly   411 GFEIFQKNSFEQFCINFCNEKLQQLFIELTLKSEQDEYRREGIEWIPVEYFDNKVICNLIEEKHK 475
            |||:|:.|||||||||:||||||||||.:|||:||:||..|||||.||:|||||:||:|||||:|
 Frog   399 GFEVFETNSFEQFCINYCNEKLQQLFISMTLKAEQEEYEIEGIEWEPVQYFDNKIICDLIEEKYK 463

  Fly   476 GIISILDEECLRPGEPTDKTFLEKLTQKLAQHHHYVCHEKAPAHIKKIMLRDEFRLVHYAGEVTY 540
            |||:|:|||||||||.||.:||.||.:|:..|.|::..:.|....:|.:...:|||:||||||||
 Frog   464 GIIAIMDEECLRPGEATDLSFLAKLEEKVGDHPHFLTRKLADPVARKTIDWVDFRLIHYAGEVTY 528

  Fly   541 SVNGFLDKNNDLLFRDLKETLSKAGNGIVRNCFPEKELRSLKRPETAITQFRASLNNLMDILMCK 605
            ...|||:||||||:|:|||.:.|:.|.|:|:||...||.:.:||||..|||:.||::|::||:.|
 Frog   529 CAVGFLEKNNDLLYRNLKEVVLKSKNYILRDCFHPTELDNRRRPETVTTQFKNSLSSLIEILLLK 593

  Fly   606 EPSYIRCIKPNDLQTANVFNDELVLHQVKYLGLMENLRVRRAGFAYRRTYELFLERYKSLSKSTW 670
            ||:||||||||:.:....|.|.||.||||||||||:||||||||||||.||:||||||||...||
 Frog   594 EPTYIRCIKPNNTKQPGKFEDMLVRHQVKYLGLMEHLRVRRAGFAYRRKYEIFLERYKSLCPQTW 658

  Fly   671 PNYKGPGGPKAGVQQLVKDLGWDEEKYRVGETKLFIRWPRTLFDTEDAYQEKKHEIAAIIQAHWK 735
            ||:.||.  :.||::|||.||:...:|::|.||||||:|||||.|.|:::.:||::.:.|||.:|
 Frog   659 PNWAGPA--REGVEKLVKYLGYQPNEYKLGRTKLFIRFPRTLFATVDSFEIRKHQLVSKIQAKYK 721

  Fly   736 GLMQRRKYLKLRAQVIIMQSYCRRKLAQQAAKKRREAADKIRAFIKGFITRNDAPNGFNEEFIAN 800
            |.:.:|.:.|.:...|.::|..|..||::.||||..|...||.||.|||.|.:.....|:.|...
 Frog   722 GCLGKRAFEKKKKAAIKLESCWRGVLARREAKKRAWAVQTIRKFIVGFINRKNPDADTNKNFFGM 786

  Fly   801 AKRMWLLRLAKELPTKVLDKSWPHAPGHCEEASGILHRLHRLHLARIYRLKLTPQQKRQFELKVL 865
            ....:|.:|.:.:|..||||.|...|...|:.|.:||:|...:|.|.|...:|||:..|.:.||:
 Frog   787 MYYNYLWKLREHVPKNVLDKRWLTPPVAMEKTSELLHKLCIRNLVRKYCRTITPQRTHQLQQKVV 851

  Fly   866 AEKVFKGKKNNYASSVSTWFQEDRIPKEHIQRVNDFVASTFGSEQLKYQSFCTKFDRHGYKSRDR 930
            ..::|||||..|..|:...|:|.|:.:   |.:|..|......:::||.....|:||||:|:|.|
 Frog   852 TSQIFKGKKEGYKQSLCQPFEETRLSE---QDINPKVLQLMNYDRIKYGIAAVKYDRHGFKARPR 913

  Fly   931 FILLSNKAIYVLDGKTYKQKHRLPLDKIDF------TLTNHNDDLMVIRIPLDLKKDKGDLILII 989
            .:||:..|.||.:....||       ||::      :::|.||..::|.:..:..|.|||.||..
 Frog   914 QLLLTQSAAYVTEQAKIKQ-------KIEYSGLKGISVSNLNDGFLIIHVSPEDNKQKGDAILQC 971

  Fly   990 PRIIEFSTYIIDTVGTASIVSIVDRNSLEHNVVKGKGGVIDIQTGAEPGVVRDK-GHLVI 1048
            ..|.|..|.:.........|:|...:...|  .:||.|:||...|||..|.:.| |||.:
 Frog   972 DHIFEAVTKLCMLASKQDAVTIAQGSLTFH--FQGKEGIIDFTHGAEAQVYKAKNGHLTV 1029

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Myo61F	NP_476934.2	MYSc	32..720	CDD:214580	403/688 (59%)
		MYSc_Myo1	52..707	CDD:276829	382/655 (58%)
		Myosin_TH1	863..1035	CDD:283635	55/177 (31%)
myo1h	XP_017945451.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	828	1.000	Domainoid score	I66
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1045	1.000	Inparanoid score	I263
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D105718at33208
OrthoFinder	1	1.000	-	-		FOG0000187
OrthoInspector	1	1.000	-	-		otm47630
Panther	1	1.100	-	-	O	PTHR13140
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2957
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160