Sequence 1: | NP_001261249.1 | Gene: | Herc4 / 38151 | FlyBaseID: | FBgn0035207 | Length: | 1062 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001034568.1 | Gene: | AREL1 / 9870 | HGNCID: | 20363 | Length: | 823 | Species: | Homo sapiens |
Alignment Length: | 637 | Identity: | 141/637 - (22%) |
---|---|---|---|
Similarity: | 246/637 - (38%) | Gaps: | 142/637 - (22%) |
- Green bases have known domain annotations that are detailed below.
Fly 516 ESMRLYLLLPL-----YHEFVNSKHYKSLQVPFANA---IFKLAENPRKVLNKWLAQTPAE-YFE 571
Fly 572 HLVQNFLH---VVIHIISFKMGLAAASPS--AERRQQLLPYNTEL-EIILKLMKTLCQINNERHD 630
Fly 631 RLNYQIFYWPDLSDYADVQQEYVKWIMADTARDFNIC---NYSFIF-DQSAKTALLQADQALQ-- 689
Fly 690 ------------------MHSAMANAATM--AFSFFNYGM-------PISQFIVLNVTRENLVQD 727
Fly 728 SLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFKEYEQSRLLWFAD 792
Fly 793 LTFETEN--------MYFLIGVLCGLAIYNFT-------IINLPFPLALFKKLLGKPVDLSDLR- 841
Fly 842 -----QLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKC-----------LKPNGN 890
Fly 891 EIAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNEDY-- 953
Fly 954 -DWQA----LQDNCEYREGYTSVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIPIQGMKAL-- 1011
Fly 1012 KLTIQPTPDERFLPVAHTCFNLLDLPRYKTKERLKYKLLQAIQQ-TQGFSLV 1062 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Herc4 | NP_001261249.1 | RCC1 | 6..55 | CDD:278826 | |
RCC1 | 59..110 | CDD:278826 | |||
RCC1 | 114..163 | CDD:278826 | |||
RCC1 | 167..218 | CDD:278826 | |||
RCC1 | 221..270 | CDD:278826 | |||
RCC1 | 273..322 | CDD:278826 | |||
RCC1_2 | 309..339 | CDD:290274 | |||
RCC1 | 327..390 | CDD:278826 | |||
HECTc | 715..1060 | CDD:238033 | 100/386 (26%) | ||
HECTc | 739..1059 | CDD:214523 | 91/361 (25%) | ||
AREL1 | NP_001034568.1 | Filamin | 52..158 | ||
Filamin | 56..154 | CDD:395505 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 315..345 | 4/29 (14%) | |||
Interaction with SOCS2. /evidence=ECO:0000269|PubMed:31578312 | 483..789 | 80/333 (24%) | |||
HECTc | 486..820 | CDD:214523 | 91/361 (25%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |