Protein Alignment Herc4 and PRAF1

DIOPT Version :10

• Sequence 1: NP_001261249.1
• Gene: Herc4 / 38151
• FlyBaseID: FBgn0035207
• Length: 1062
• Species: Drosophila melanogaster
• Sequence 2: NP_565144.1
• Gene: PRAF1 / 844030
• AraportID: AT1G76950
• Length: 1103
• Species: Arabidopsis thaliana
• Alignment Length: 805
• Identity: 179/805 - (22%)
• Similarity: 317/805 - (39%)
• Gaps: 143/805 - (17%)

  Fly     6 ELYCWGSTSHGQLGLGGIEDE--------QILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVY 62
            ::|.||......:...||:..        .:|.|..:.......|.|:|||.||..|:|..|:::
plant   239 DVYIWGEVICDNVVKVGIDKNASYLTTRTDVLVPKPLESNIVLDVHQIACGVRHAAFVTRQGEIF 303

  Fly    63 ACGSNDYSQLGHDL--PTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGD--ND 123
            ..|.....:|||.:  ....||:...|......|:|    .||..|:.|::..|::.:|||  ::
plant   304 TWGEESGGRLGHGIGKDVFHPRLVESLTATSSVDFV----ACGEFHTCAVTLAGELYTWGDGTHN 364

  Fly   124 CGQLGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDL 188
            .|.|||.:|.......::...|....|..::||..|:..:||.|.|:::|...:|.||   ..|.
plant   365 VGLLGHGSDISHWIPKRIAGSLEGLHVASVSCGPWHTALITSYGRLFTFGDGTFGVLG---HGDK 426

  Fly   189 THCNYPLRLTTLLGIPLAAIACGGNHSFLISK------------SGAVFGWGRNNCGQLGLNDET 241
            ....||..:.:|.|:...|::||..|:..:.:            ||.:|.||..:..:||..|:.
plant   427 ETVQYPREVESLSGLRTIAVSCGVWHTAAVVEIIVTQSNSSSVSSGKLFTWGDGDKNRLGHGDKD 491

  Fly   242 NRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELMG 306
            .|..||.:..|.......:|||...:|.||..|.|||.|:..|||||: ..::..||.:|.:.:.
plant   492 PRLKPTCVPALIDYNFHKIACGHSLTVGLTTSGQVFTMGSTVYGQLGN-LQTDGKLPCLVEDKLA 555

  Fly   307 ST-ITQVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGPWVSPSGSALLQ-- 368
            |. :.:::||..|..||. ||..||.:|.|::|:||....:...:|.:|         .||..
plant   556 SEFVEEISCGAYHVAALT-SRNEVYTWGKGANGRLGHGDLEDRKVPTIV---------EALKDRH 610

  Fly   369 ------SNDSQVSLVIRQIFSGGDQSIVTTTLFVDKVPPEDFRNYNPKSQILTLTAEVTKQCAQC 427
                  .::...::.:.:..||.:||..:|.........:....||..          ...|..|
plant   611 VKYIACGSNYTAAICLHKWVSGAEQSQCSTCRLAFGFTRKRHNCYNCG----------LVHCHSC 665

  Fly   428 KQGLQSDMDLLSSIELIFR-SQACW----NGSFLLDHDRHFGCSVRNHG-----LDLKAAQLA-- 480
            .........|..|...::| ..:|:    ..|.:.|.:|......|..|     ||....:||
plant   666 SSKKAFRAALAPSAGRLYRVCDSCYVKLSKVSEINDTNRRNSAVPRLSGENRDRLDKSEIRLAKF 730

  Fly   481 ----FDNLRAVENESIRQ-----------------------VIWDNI--TKELVGSLVCSPADVE 516
                .|.::.:::::.:|                       .:..||  .:.....|..:|:.:.
plant   731 GTSNMDLIKQLDSKAAKQGKKTDTFSLGRNSQLPSLLQLKDAVQSNIGDMRRATPKLAQAPSGIS 795

  Fly   517 SMRLYLLLPLYHEFVNSKHYKSLQVPFANAIF---KLAENPRK---VLNKWLAQ---------TP 566
            |..   :.|....  :|....:..:|..:.::   .:|:|.:|   :||:.:.:         ..
plant   796 SRS---VSPFSRR--SSPPRSATPMPSTSGLYFPVGIADNMKKTNEILNQEIVKLRTQVDSLTQK 855

  Fly   567 AEYFEHLVQNFLHVVIHIISFKMGLAAASPSAERRQQLLPYNTELEIILKL-----MKTLCQINN 626
            .|:.|..:||.:......::.....:|.|.:|:...:.|....: ::..||     :|..|..|.
plant   856 CEFQEVELQNSVKKTQEALALAEEESAKSRAAKEAIKSLIAQLK-DVAEKLPPGESVKLACLQNG 919

  Fly   627 ERHDRLNYQIFYWPDLSDYADVQQEYVKWIMADTAR-DFNICNYSFIFDQSAK---------TAL 681
                 |:...|::|:.:.:...:.|.:...::..|. ||...|.|:...||.|         :..
plant   920 -----LDQNGFHFPEENGFHPSRSESMTSSISSVAPFDFAFANASWSNLQSPKQTPRASERNSNA 979

  Fly   682 LQADQALQMHSAMANAATMAFSFFN 706
            ..||..|....::.:.....|.|.|
plant   980 YPADPRLSSSGSVISERIEPFQFQN 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	ATS1	7..352	CDD:444065	107/369 (29%)
		RCC1	327..390	CDD:395335	15/70 (21%)
		HECTc	715..1060	CDD:238033
PRAF1	NP_565144.1	PH_PLC_plant-like	14..124	CDD:270171
		ATS1	285..624	CDD:444065	103/356 (29%)
		FYVE	627..695	CDD:214499	13/77 (17%)
		COG1340	<828..909	CDD:440951	15/81 (19%)
		BRX_N	879..>908	CDD:404581	6/29 (21%)
		BRX	1022..1077	CDD:429960