DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and AT5G16040

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_197108.1	Gene:	AT5G16040 / 831461	AraportID:	AT5G16040	Length:	396	Species:	Arabidopsis thaliana

Alignment Length:	402	Identity:	133/402 - (33%)
Similarity:	198/402 - (49%)	Gaps:	32/402 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGKELYCWGSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACG 65
            |||...:..|||...||||||..|::::  .|.:.......|:.|..|.|::|.:...||::..|
plant     1 MASATSVIAWGSGEDGQLGLGTDEEKEL--ASVVDALEPFNVRSVVGGSRNSLAICDDGKLFTWG 63

  Fly    66 SNDYSQLGHDLPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLGHA 130
            .|....|||. |..:...:| .|:..|.:..|:|...|..|.||:.|.|:..:||.|:.||.|..
plant    64 WNQRGTLGHP-PETKTESTP-SLVKSLANVKIVQAAIGGWHCLAVDDQGRAYAWGGNEYGQCGEE 126

  Fly   131 TDKEIVQLPKVVRQLVTK-------TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDL 188
            ..|:....| |.|.:|..       ||.|:|.|..||:.||..|.:::||...       .|.|:
plant   127 PSKDETGRP-VRRDIVIPKRCAQQLTVRQVAAGGTHSVVLTREGYVWTWGQPW-------PPGDI 183

  Fly   189 THCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKTLR 253
            ...:.|:|:..|..:.|  ||.|..|:..:.:.|.::.||.|..||||..|...||||..::.|.
plant   184 KQISVPVRVQGLENVRL--IAVGAFHNLALKEDGTLWAWGNNEYGQLGTGDTQPRSYPIPVQGLD 246

  Fly   254 TLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFS--SNEMLPRMVMELMGSTITQVACGN 316
            .|.:..:|.|...|..|||||.|:..|.|.:|:||.|.:  |::|||:.|..|.|..|.||:||.
plant   247 DLTLVDIAAGGWHSTALTNEGEVYGWGRGEHGRLGFGDNDKSSKMLPQKVNLLAGEDIIQVSCGG 311

  Fly   317 RHTLALVPSRGRVYAFGLGSSGQLG----TRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQVSLV 377
            .|::||... ||:::||.|..|:||    ..:.:.|.|| :.|.|   |.|.......:.....:
plant   312 THSVALTRD-GRIFSFGRGDHGRLGYGRKVTTGQPLELP-IHIPP---PEGRFNHTDEEDDGKWI 371

  Fly   378 IRQIFSGGDQSI 389
            .:.:..||..::
plant   372 AKHVACGGRHTL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	16/48 (33%)
		RCC1	59..110	CDD:278826	16/50 (32%)
		RCC1	114..163	CDD:278826	19/55 (35%)
		RCC1	167..218	CDD:278826	13/50 (26%)
		RCC1	221..270	CDD:278826	18/48 (38%)
		RCC1	273..322	CDD:278826	22/50 (44%)
		RCC1_2	309..339	CDD:290274	13/29 (45%)
		RCC1	327..390	CDD:278826	17/67 (25%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
AT5G16040	NP_197108.1	ATS1	6..339	CDD:227511	121/347 (35%)
AT5G16040	NP_197108.1	RCC1	320..385	CDD:395335	17/69 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1192
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45622
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020