DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and AT5G11580

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_568250.1	Gene:	AT5G11580 / 831030	AraportID:	AT5G11580	Length:	553	Species:	Arabidopsis thaliana

Alignment Length:	423	Identity:	105/423 - (24%)
Similarity:	158/423 - (37%)	Gaps:	120/423 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 VACGHRHTLFLTATGKVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYV---------IIQI 100
            :|.|..||:.||..|.||:.|...:.:||....:..       |:|.|.::.         |:.:
plant    21 LAAGEAHTIALTGDGCVYSWGRGMFGRLGTGKESDE-------LVPVLVEFPNQAEGDRIRIVGV 78

  Fly   101 CCGSRHSLALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTK----------------- 148
            ..|:.||||:||.|.|..||.|..||||.  |.|....|.:::.|..:
plant    79 AAGAYHSLAVSDDGSVWCWGYNIYGQLGF--DGENSLAPCLIKNLFERETSSSSLNDSGREVGSD 141

  Fly   149 -TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPN-DLTHCNYPLRLTTLLGIPLAAIACG 211
             .|..:..|:..|||:.:.|.|:.|| |:..|.....|. ..|....|..:....|..:..:|||
plant   142 LKVCTVKAGSMMSLAIDNVGGLWMWG-NVPPQDSEPDPRLSFTSIPIPFPILDFHGRTVLKVACG 205

  Fly   212 GNHSFLISKSG-----------AVFGWGRNNCGQLGLNDETNRSYPTQLKTLRT---LGVRFVAC 262
            ..|...:...|           .::.||.|:.|||||.|..:|:.|..::|...   |.|..:||
plant   206 DEHVVALVGPGDIHKDNSYDVSVLYSWGNNHHGQLGLGDGESRARPQTVETFNQKSGLTVYDIAC 270

  Fly   263 GDEFSVFLT-------NEGGVFTCGAGAYGQLGHGFSSNEMLPRMVMELM--------------- 305
            |...:..||       .....:|.|.|..|||||..:.:..||..|.:|.
plant   271 GAHHTALLTYRKETPKGPSICWTFGFGENGQLGHRSNKSSSLPEPVSDLPEHAYLVSVDCGLFHT 335

  Fly   306 ------------------------------------------GST----ITQVACGNRHTLALVP 324
                                                      ||:    ..||:||..||:.:|.
plant   336 SVVSSEGYVWSWGMERGLGLCPDVNFTEVEAGDDSVPRKISGGSSRFRDPVQVSCGAAHTVLVVD 400

  Fly   325 SRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGP 357
            ...:::::|.|.:|.|||.:.....:|.:|..|
plant   401 GGYKLWSWGRGRNGVLGTGNVSDCYVPTLVFWP 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	4/9 (44%)
		RCC1	59..110	CDD:278826	14/59 (24%)
		RCC1	114..163	CDD:278826	17/66 (26%)
		RCC1	167..218	CDD:278826	14/51 (27%)
		RCC1	221..270	CDD:278826	18/62 (29%)
		RCC1	273..322	CDD:278826	20/109 (18%)
		RCC1_2	309..339	CDD:290274	9/29 (31%)
		RCC1	327..390	CDD:278826	9/31 (29%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
AT5G11580	NP_568250.1	ATS1	27..443	CDD:227511	103/417 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920