DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and RUG1

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_680156.2	Gene:	RUG1 / 830771	AraportID:	AT5G08710	Length:	434	Species:	Arabidopsis thaliana

Alignment Length:	384	Identity:	123/384 - (32%)
Similarity:	181/384 - (47%)	Gaps:	52/384 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SGKELYC-WGSTSHGQLGLGGIEDEQILTPSQIPWTP-------DTAVQQVACGHRHTLFLTATG 59
            |||.... |||..:|:||||.::.:         |||       |.::..||||..||||||.|.
plant    46 SGKRFAAMWGSGDYGRLGLGNLDSQ---------WTPAVCSALSDHSITAVACGGAHTLFLTETR 101

  Fly    60 KVYACGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDC 124
            :|:|.|.||..|||.. ..|...|.| |.:..| |..|:.|..|..||.|::..|::..||.|..
plant   102 RVFATGLNDCGQLGVS-DVKSHAMDP-LEVSGL-DKDILHISAGYYHSAAITVDGELYMWGKNSS 163

  Fly   125 GQLGHATD-KEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLG------- 181
            ||||.... ..:|::|..|..|...|:..:|.|:.||:|:|..||:.|||....|:||
plant   164 GQLGLGKKAARVVRVPTKVEALHGITIQSVALGSEHSVAVTDGGEVLSWGGGGSGRLGHGHQSSL 228

  Fly   182 ---VNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNR 243
               :.|.::.|    |..:..|.||.:..:|.|..||....::|:.|.:|..:..::|.....|.
plant   229 FGILRSNSEFT----PRLIKELEGIKVTNVAAGLLHSACTDENGSAFMFGEKSINKMGFGGVRNA 289

  Fly   244 SYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLP-RMVMELMGS 307
            :.|:.:..:..  ...||||...:..:|..|.::|.|:...|.||...:.....| |:....:.|
plant   290 TTPSIISEVPY--AEEVACGGYHTCVVTRGGELYTWGSNENGCLGTDSTYVSHSPVRVEGPFLES 352

  Fly   308 TITQVACGNRHTLALVPSRGRVYAFGLG------------SSGQLGTRSTKSLMLPQVV 354
            |::||:||.:||.|:  |...|:.:|.|            |.||||..|......|.:|
plant   353 TVSQVSCGWKHTAAI--SDNNVFTWGWGGSHGTFSVDGHSSGGQLGHGSDVDYARPAMV 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	19/56 (34%)
		RCC1	59..110	CDD:278826	19/50 (38%)
		RCC1	114..163	CDD:278826	17/49 (35%)
		RCC1	167..218	CDD:278826	18/60 (30%)
		RCC1	221..270	CDD:278826	10/48 (21%)
		RCC1	273..322	CDD:278826	16/49 (33%)
		RCC1_2	309..339	CDD:290274	12/41 (29%)
		RCC1	327..390	CDD:278826	11/40 (28%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
RUG1	NP_680156.2	RCC1	54..97	CDD:395335	19/51 (37%)
RUG1	NP_680156.2	ATS1	93..432	CDD:227511	104/328 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920