DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and AT3G23270

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_001327882.1	Gene:	AT3G23270 / 821906	AraportID:	AT3G23270	Length:	1054	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	141/527 - (26%)
Similarity:	221/527 - (41%)	Gaps:	116/527 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 ELYCWGST-SHGQLGLGGIEDE----QILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACG 65
            ::|.||.. :.|.|..|...:|    .:|||..:.......|.|:.||.||...:|..|:|:..|
plant   216 DVYVWGEVWTEGILPDGTASNETVKTDVLTPRPLESNVVLDVHQIVCGVRHVALVTRQGEVFTWG 280

  Fly    66 SNDYSQLGHDLPT--KRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGD--NDCGQ 126
            .....:|||.:..  .||::..||.:..: |:|    .||..|:..:|..|.:.||||  ::.|.
plant   281 EEVGGRLGHGIQVDISRPKLVEFLALTNI-DFV----ACGEYHTCVVSTSGDLFSWGDGIHNVGL 340

  Fly   127 LGHATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHC 191
            |||.:|.......:|...|....|:.:|||..||...|:.|:|:::|...:|.||..:...:
plant   341 LGHGSDISHWIPKRVSGPLEGLQVLSVACGTWHSALATANGKLFTFGDGAFGVLGHGNRESV--- 402

  Fly   192 NYPLRLTTLLGIPLAAIACGGNHSFLI----------SKSGAVFGWGRNNCGQLGLNDETNRSYP 246
            :||..:.:|.|:....:||...|:..|          ..|..:|.||..:..:||..::.....|
plant   403 SYPKEVQSLNGLKTVKVACSIWHTAAIVEVMGQTATSMSSRKLFTWGDGDKNRLGHGNKETYLLP 467

  Fly   247 TQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFSSNEMLPRMVME-LMGSTIT 310
            |.:.:|.......:|||..|:|.||..|.|||.|..|:||||:..|..: ||.:|.: |:|..:.
plant   468 TCVSSLIDYNFHKIACGHTFTVALTTSGHVFTMGGTAHGQLGNSISDGK-LPCLVQDRLVGEFVE 531

  Fly   311 QVACGNRHTLALVPSRGRVYAFGLGSSGQLGTRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQV- 374
            ::|||..| :|::.||..|:.:|.|::|:||...|:....|.:|         .||   .|..|
plant   532 EIACGAHH-VAVLTSRSEVFTWGKGANGRLGHGDTEDKRTPTLV---------EAL---RDRHVK 583

  Fly   375 ----------SLVIRQIFSGGDQSIVTTTLFVDKVPPEDFRNYNPKSQILTLTAEVTKQCAQCKQ 429
                      |:.|.:..||.||||                                  |:.|:|
plant   584 SLSCGSNFTSSICIHKWVSGADQSI----------------------------------CSGCRQ 614

  Fly   430 GLQSDMDLLSSIELIFRSQACWNGSFLLDHDRHFGCSVRNHGLDLKAA------------QLAFD 482
                      :.....:...|:|...:..|    .||.:.   .||||            ...:.
plant   615 ----------AFGFTRKRHNCYNCGLVHCH----ACSSKK---ALKAALAPTPGKPHRVCDACYS 662

  Fly   483 NLRAVEN 489
            .|:|.|:
plant   663 KLKAAES 669

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	16/53 (30%)
		RCC1	59..110	CDD:278826	15/52 (29%)
		RCC1	114..163	CDD:278826	18/50 (36%)
		RCC1	167..218	CDD:278826	13/50 (26%)
		RCC1	221..270	CDD:278826	14/48 (29%)
		RCC1	273..322	CDD:278826	20/49 (41%)
		RCC1_2	309..339	CDD:290274	10/29 (34%)
		RCC1	327..390	CDD:278826	20/73 (27%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
AT3G23270	NP_001327882.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920