DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and AT3G02510

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_186900.3	Gene:	AT3G02510 / 821100	AraportID:	AT3G02510	Length:	393	Species:	Arabidopsis thaliana

Alignment Length:	404	Identity:	124/404 - (30%)
Similarity:	194/404 - (48%)	Gaps:	36/404 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MASGKELYCWGSTSHGQLGLGGIEDEQ--ILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYA 63
            |.:...:..|||...||||:|..|:::  .:..:..|:    :|:.|..|.|::|.:...|.::.
plant     1 MVTATSIIAWGSGEDGQLGIGTNEEKEWACVVEALEPY----SVRSVVSGSRNSLAICDDGTMFT 61

  Fly    64 CGSNDYSQLGHDLPTKRPRMSPFLLIPELQDYVIIQICCGSRHSLALSDWGQVLSWGDNDCGQLG 128
            .|.|....|||...||...:..  .:..|.:..|.|...|..|.||:.|.|:..:||.|:.||.|
plant    62 WGWNQRGTLGHQPETKTENIPS--RVKALANVKITQAAIGGWHCLAVDDQGRAYAWGGNEYGQCG 124

  Fly   129 HATDKEIVQLPKVVRQLVTK-------TVVQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPN 186
            ....|:.:..| |.|.:|..       ||.|:|.|..||:.||..|.:::||...       .|.
plant   125 EEPLKDEMGRP-VRRDIVIPKRCAPKLTVRQVAAGGTHSVVLTREGHVWTWGQPW-------PPG 181

  Fly   187 DLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLKT 251
            |:...:.|:|:..|..:.|  ||.|..|:..:.:.|.:..||.|..||||..|....|:|..::.
plant   182 DIKQISVPVRVQGLENVRL--IAVGAFHNLALEEDGRLLAWGNNEYGQLGTGDTQPTSHPVPVQG 244

  Fly   252 LRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLGHGFS--SNEMLPRMVMELMGSTITQVAC 314
            |..|.:..:|.|...|..||::|.|:..|.|.:|:||.|.:  |::|:|:.|..|....|.||:|
plant   245 LDDLTLVDIAAGGWHSTALTDKGEVYGWGRGEHGRLGLGDNDKSSKMVPQKVNLLAEEDIIQVSC 309

  Fly   315 GNRHTLALVPSRGRVYAFGLGSSGQLG----TRSTKSLMLPQVVIGPWVSPSGSALLQSNDSQVS 375
            |..|::||... ||:::||.|..|:||    ..:.:.|.|| :.|.|   |.||......:.:..
plant   310 GGTHSVALTRD-GRIFSFGRGDHGRLGYGRKVTTGQPLELP-IKIPP---PEGSFNHTDEEEEGK 369

  Fly   376 LVIRQIFSGGDQSI 389
            ...:.|..||..::
plant   370 WSAKSIACGGRHTL 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	15/50 (30%)
		RCC1	59..110	CDD:278826	14/50 (28%)
		RCC1	114..163	CDD:278826	19/55 (35%)
		RCC1	167..218	CDD:278826	13/50 (26%)
		RCC1	221..270	CDD:278826	16/48 (33%)
		RCC1	273..322	CDD:278826	19/50 (38%)
		RCC1_2	309..339	CDD:290274	13/29 (45%)
		RCC1	327..390	CDD:278826	19/67 (28%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
AT3G02510	NP_186900.3	ATS1	6..387	CDD:227511	123/399 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1062377at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm1192
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45622
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020