DRSC/TRiP Functional Genomics Resources

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Protein Alignment Herc4 and plekha7a

DIOPT Version :9

Sequence 1:NP_001261249.1 Gene:Herc4 / 38151 FlyBaseID:FBgn0035207 Length:1062 Species:Drosophila melanogaster
Sequence 2:NP_001129715.1 Gene:plekha7a / 571486 ZFINID:ZDB-GENE-050419-75 Length:1197 Species:Danio rerio


Alignment Length:258 Identity:51/258 - (19%)
Similarity:81/258 - (31%) Gaps:95/258 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly   709 MPISQFIVLNVTRENL----VQDSLRELQH-YSQSDLK------------KPLKIKFHGEEAEDA 756
            ||.|.:|...|:..:|    ..|:...|:. ....|||            ||:|:      ||..
Zfish   608 MPPSAYITHTVSAPSLRGKTADDTYMHLKKGLEYLDLKVSGTEALKGRPAKPVKV------AESD 666

  Fly   757 GGV-------------RKEFFMLLLKD-------LLDPKYGMFKEYEQSRLLWFADLTFETENMY 801
            ..|             ..||.:..|||       :||..:...::|:        |....|:.  
Zfish   667 VDVTLSRLCEQDKILQELEFRLSGLKDDKDKLESVLDVSHQQMEQYK--------DQPSHTDK-- 721

  Fly   802 FLIGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSDLR-QLSPPEANSMQSLLDYQGDDFKEV 865
                                  :|..::||.:  ||..:| .:|.......::..||.|      
Zfish   722 ----------------------IAYQQRLLQE--DLVHIRADISRVSTEMERAWDDYSG------ 756

  Fly   866 FDLTFEISRDVFGEAETKCLKPNG-----------NEIAVTLENRQEFVDLYVDFVFNKSVEL 917
            .:.:.|..|||.....|.|..|..           .::...|.:.:|...:.||.|.|...:|
Zfish   757 MEQSVEQLRDVLQTQMTLCTSPQEKNQLKRELWRMEDVMTGLSSTKETFKITVDSVKNPERKL 819

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Herc4NP_001261249.1 RCC1 6..55 CDD:278826
RCC1 59..110 CDD:278826
RCC1 114..163 CDD:278826
RCC1 167..218 CDD:278826
RCC1 221..270 CDD:278826
RCC1 273..322 CDD:278826
RCC1_2 309..339 CDD:290274
RCC1 327..390 CDD:278826
HECTc 715..1060 CDD:238033 48/252 (19%)
HECTc 739..1059 CDD:214523 43/223 (19%)
plekha7aNP_001129715.1 WW 55..84 CDD:278809
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 98..148
PH_PEPP1_2_3 153..256 CDD:270068
PH 159..255 CDD:278594
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 348..384
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 423..467
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 508..577
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 830..928
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1032..1064
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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