DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and plekha5

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	XP_021330752.1	Gene:	plekha5 / 567300	ZFINID:	ZDB-GENE-041210-25	Length:	1398	Species:	Danio rerio

Alignment Length:	163	Identity:	35/163 - (21%)
Similarity:	64/163 - (39%)	Gaps:	46/163 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   718 NVTRENLVQDSLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLK---DLLDPKYGMF 779
            |:|.::|...:..||         ..|.||...::|| ...:|:.....|::   |..:||..:.
Zfish   730 NITAQSLQGKTPEEL---------TLLLIKLRRQQAE-LNSLREHTLAQLMQLNLDATNPKSEIL 784

  Fly   780 KEYEQSRLLWFADLTFETENMYFLIGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSDLRQLS 844
            ..:.|..|::......|.|.:.|:|..:    |.|    :.|.| .|::            :|:|
Zfish   785 SHHLQRNLMYLDSQMKENEPIIFMIHTM----IEN----SAPRP-QLYQ------------QQMS 828

  Fly   845 PPEANSMQSLLDYQGDDF---KEVFDLTFEISR 874
            |.|         |:.:.:   .|..|:..::||
Zfish   829 PEE---------YRENTYMYRPEELDVDAKLSR 852

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826
		RCC1	59..110	CDD:278826
		RCC1	114..163	CDD:278826
		RCC1	167..218	CDD:278826
		RCC1	221..270	CDD:278826
		RCC1	273..322	CDD:278826
		RCC1_2	309..339	CDD:290274
		RCC1	327..390	CDD:278826
		HECTc	715..1060	CDD:238033	35/163 (21%)
		HECTc	739..1059	CDD:214523	30/142 (21%)
plekha5	XP_021330752.1	WW	13..42	CDD:306827
		WW	58..87	CDD:306827
		PH_PEPP1_2_3	177..280	CDD:270068
		SMC_N	822..>983	CDD:330553	10/52 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900