| Sequence 1: | NP_001261249.1 | Gene: | Herc4 / 38151 | FlyBaseID: | FBgn0035207 | Length: | 1062 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001271267.1 | Gene: | NEDD4 / 4734 | HGNCID: | 7727 | Length: | 1319 | Species: | Homo sapiens |
| Alignment Length: | 359 | Identity: | 118/359 - (32%) |
|---|---|---|---|
| Similarity: | 199/359 - (55%) | Gaps: | 23/359 - (6%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 717 LNVTRENLVQDSLRELQHYSQSD-LKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFK 780
Fly 781 EYEQS-----RLLWFADLTFETENMYF-LIGVLCGLAIYNFTIINLPFPLALFKKLLGKPVDLSD 839
Fly 840 LRQLSPPEANSMQSLLDYQGDDFKEVFDLTFEISRDVFGEAETKCLKPNGNEIAVTLENRQEFVD 904
Fly 905 LYVDFVFNKSVELHYNAFHKGFMKVCSGRVIHIFQPEELMAVVVGNEDYDWQALQDNCEYREGYT 969
Fly 970 SVDDTIKWFWEVIHDMSEAEKKSFLLFLTGSDRIPIQGMKAL-------KLTIQP--TPDERFLP 1025
Fly 1026 VAHTCFNLLDLPRYKTKERLKYKLLQAIQQTQGF 1059 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Herc4 | NP_001261249.1 | RCC1 | 6..55 | CDD:278826 | |
| RCC1 | 59..110 | CDD:278826 | |||
| RCC1 | 114..163 | CDD:278826 | |||
| RCC1 | 167..218 | CDD:278826 | |||
| RCC1 | 221..270 | CDD:278826 | |||
| RCC1 | 273..322 | CDD:278826 | |||
| RCC1_2 | 309..339 | CDD:290274 | |||
| RCC1 | 327..390 | CDD:278826 | |||
| HECTc | 715..1060 | CDD:238033 | 118/359 (33%) | ||
| HECTc | 739..1059 | CDD:214523 | 112/335 (33%) | ||
| NEDD4 | NP_001271267.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 204..229 | ||
| C2 | <517..570 | CDD:417471 | |||
| Mediates interaction with TNIK. /evidence=ECO:0000250 | 578..981 | 4/16 (25%) | |||
| WW | 611..643 | CDD:197736 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 755..780 | ||||
| WW | 769..798 | CDD:395320 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 796..834 | ||||
| WW | 842..871 | CDD:395320 | |||
| WW | 893..925 | CDD:197736 | |||
| HECTc | 986..1315 | CDD:214523 | 112/335 (33%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5021 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 3 | 2.810 | |||||