DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and yki

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_001350857.1	Gene:	yki / 37851	FlyBaseID:	FBgn0034970	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	165	Identity:	38/165 - (23%)
Similarity:	60/165 - (36%)	Gaps:	38/165 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 LLIPELQDYVIIQICCGSRHSL-ALSDWGQVLSWGDNDCGQLGHATDKEIVQLPKVVRQLVTKTV 150
            :|.|...:.:::::...:..:| ||.|  .||:.||          .|..:|||..:|:|.....
  Fly    47 MLSPIKSNNLVVRVNQDTDDNLQALFD--SVLNPGD----------AKRPLQLPLRMRKLPNSFF 99

  Fly   151 VQIACGNNHSLALTSCGELYSWGSNIYGQLGVNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHS 215
            ...|  .:||.| .|....|..||    |..:|..|..:....|...:.:..||...|.....||
  Fly   100 TPPA--PSHSRA-NSADSTYDAGS----QSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHS 157

  Fly   216 FLISKSGAVFGWGRNNCGQLGLNDETNRSYPTQLK 250
                              :|.::....||.|..|:
  Fly   158 ------------------RLAIHHSRARSSPASLQ 174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826
		RCC1	59..110	CDD:278826	3/23 (13%)
		RCC1	114..163	CDD:278826	13/48 (27%)
		RCC1	167..218	CDD:278826	12/50 (24%)
		RCC1	221..270	CDD:278826	5/30 (17%)
		RCC1	273..322	CDD:278826
		RCC1_2	309..339	CDD:290274
		RCC1	327..390	CDD:278826
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354
		WW	266..295	CDD:395320
		WW	335..364	CDD:395320
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900