DRSC/TRiP Functional Genomics Resources

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Protein Alignment Herc4 and Trip12

DIOPT Version :9

Sequence 1:NP_001261249.1 Gene:Herc4 / 38151 FlyBaseID:FBgn0035207 Length:1062 Species:Drosophila melanogaster
Sequence 2:XP_038939619.1 Gene:Trip12 / 316575 RGDID:1306607 Length:2074 Species:Rattus norvegicus


Alignment Length:402 Identity:107/402 - (26%)
Similarity:177/402 - (44%) Gaps:71/402 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   719 VTRENLVQDSLRELQHYSQSDLKKPLKIKFHGEEAEDAGGVRKEFFMLLLKDLLDPKYGMFK--- 780
            |.||.|::.:...:|....|  :..|:|::..|.....|.. .||:.|:.::|.....|:::   
  Rat  1675 VNREELLKQAESVMQDLGSS--RAMLEIQYENEVGTGLGPT-LEFYALVSQELQRADLGLWRGEE 1736

  Fly   781 -------------EYEQSRLLWFADLTF----------ETENMYFLIGVLCGLAIYNFTIINLPF 822
                         :|.|:....|| |.|          :.:..:..:|.|...||.:|.:::||.
  Rat  1737 VTLSNPKGSQEGTKYIQNLQGLFA-LPFGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPL 1800

  Fly   823 PLALFKKLLGKPVDLS--DLRQLSPPEANSMQSL---------LDYQGDDFKE------------ 864
            .|..:|.:|.:...|:  ||..:.|..|.|:..|         |:......||            
  Rat  1801 GLPFYKWMLRQETSLTSHDLFDIDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMN 1865

  Fly   865 ---VFDLTFEISRDVFGEAETKCLKPNGNEIAVTLENRQEFVDLYVDFVFNKSVELHYNAFHKGF 926
               |.||..:.:...|...|   ||..|.:|.||:.|.:|::.|.:.:..|:.|...:::|..||
  Rat  1866 GCSVEDLGLDFTLPGFPNIE---LKKGGKDIPVTIHNLEEYLRLVIFWALNEGVCRQFDSFRDGF 1927

  Fly   927 MKVCSGRVIHIFQPEELMAVVVGNEDYDWQA--LQDNCEYREGYTSVDDTIKWFWEVIHDMSEAE 989
            ..|.....:..|.||||..::.|::...|.|  |.:.|....|||.....:|:.:|::......:
  Rat  1928 ESVFPLSHLQYFYPEELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQ 1992

  Fly   990 KKSFLLFLTGSDRIPIQGMKALK--LTI-------QPTPDERFLPVAHTCFNLLDLPRYKTKERL 1045
            ::.||.|:|||.|:|:.|.::|.  |||       ...||: |||...||.|.|.||.|.:.|.:
  Rat  1993 QRLFLQFVTGSPRLPVGGFRSLNPPLTIVRKTFESTENPDD-FLPSVMTCVNYLKLPDYSSIEIM 2056

  Fly  1046 KYKLLQAIQQTQ 1057
            :.|||.|.::.|
  Rat  2057 RDKLLIAAREGQ 2068

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Herc4NP_001261249.1 RCC1 6..55 CDD:278826
RCC1 59..110 CDD:278826
RCC1 114..163 CDD:278826
RCC1 167..218 CDD:278826
RCC1 221..270 CDD:278826
RCC1 273..322 CDD:278826
RCC1_2 309..339 CDD:290274
RCC1 327..390 CDD:278826
HECTc 715..1060 CDD:238033 107/402 (27%)
HECTc 739..1059 CDD:214523 101/382 (26%)
Trip12XP_038939619.1 SRP1 489..>714 CDD:227396
WWE 814..876 CDD:397111
HECTc 1672..2072 CDD:238033 107/402 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.900

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