DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and Wwc1

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	XP_002727807.1	Gene:	Wwc1 / 303039	RGDID:	1308329	Length:	1108	Species:	Rattus norvegicus

Alignment Length:	101	Identity:	19/101 - (18%)
Similarity:	45/101 - (44%)	Gaps:	12/101 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   594 ASPSAERRQQLLPYNTELEIILKLMKTLCQINNERHDRLNYQIFYWPDLSDYADV-----QQEYV 653
            :|..:.|.::|:..:.:||:.|:..:|.       |.:|..:|....:|.::.:.     ::|..
  Rat   970 SSVKSLRTERLIRTSLDLELDLQATRTW-------HSQLTQEISVLKELKEHLEQAKNHGEKELP 1027

  Fly   654 KWIMADTARDFNICNYSFIFDQSAKTALLQADQALQ 689
            :|:..|......:.......|:....:.||||:.::
  Rat  1028 QWLREDERFRLLLRMLEKRVDRGEHKSELQADKMMR 1063

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826
		RCC1	59..110	CDD:278826
		RCC1	114..163	CDD:278826
		RCC1	167..218	CDD:278826
		RCC1	221..270	CDD:278826
		RCC1	273..322	CDD:278826
		RCC1_2	309..339	CDD:290274
		RCC1	327..390	CDD:278826
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
Wwc1	XP_002727807.1	WW	9..39	CDD:238122
		WW	55..84	CDD:278809
		ALDH-SF	378..>420	CDD:299846
		C2_Kibra	661..784	CDD:176062
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900