DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Herc4 and SPAC10F6.04

DIOPT Version :9

Sequence 1:	NP_001261249.1	Gene:	Herc4 / 38151	FlyBaseID:	FBgn0035207	Length:	1062	Species:	Drosophila melanogaster
Sequence 2:	NP_001342701.1	Gene:	SPAC10F6.04 / 2542973	PomBaseID:	SPAC10F6.04	Length:	351	Species:	Schizosaccharomyces pombe

Alignment Length:	394	Identity:	95/394 - (24%)
Similarity:	144/394 - (36%)	Gaps:	123/394 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GSTSHGQLGLGGIEDEQILTPSQIPWTPDTAVQQVACGHRHTLFLTATGKVYACGSNDYSQLGHD 75
            ||..:.||||.  .||.:.:|..:|:  |.|:::::||..|||.|....:::|||.|...|.|::
pombe     6 GSNGNFQLGLN--NDEDVYSPQIVPF--DRAIEKISCGGNHTLLLDEDSQLWACGDNRKGQCGYE 66

  Fly    76 LPTKRPRMSPFLLIPELQDYVII----------QICCGSRHSLAL-SDWGQVLSWGDNDCGQLG- 128
            :  |.|..:|  |.|   ||:.|          .:.||...|:.: :|..:|.|.|:...|:||
pombe    67 V--KEPLYNP--LSP---DYLRIFTRVSHERWVFLTCGWEFSVIVHADRRRVCSCGEGLSGELGQ 124

  Fly   129 ---------------HATDKEIVQLPKVVRQLVTKTVVQIACGNNHSLALTSCGELYSWGSNIYG 178
                           :..|||.              ::.|:.|..|.:.:|:.|.||..|....|
pombe   125 GNRSNSQGLREIDIPYLDDKEF--------------IIDISAGLRHWICVTNEGNLYGCGDGRKG 175

  Fly   179 QLG------VNSPNDLTHCNYPLRLTTLLGIPLAAIACGGNHSFLISKSGAVF------------ 225
            |||      ||..:.|....:           ..|:.||...|.::.::|.|.
pombe   176 QLGPVVMKTVNKVSFLGRIEH-----------AQAVVCGVQFSAVLQETGHVIVLGGEKWNVAAE 229

  Fly   226 --GWGRNNCGQLGLNDETNRSYPTQLKTLRTLGVRFVACGDEFSVFLTNEGGVFTCGAGAYGQLG 288
              .|..|       |.|.:.|..:......||.:            |:.||.|:..|.....|..
pombe   230 CDAWQAN-------NSELSSSICSISANWSTLSL------------LSTEGCVYAFGRCDRAQKA 275

  Fly   289 HGFSSNEMLPRMVMELMGSTITQVACGNRHTLALVPSRGRVYAFGLGSSGQLG------TRSTKS 347
            |              ...|.|.|:|.|..|.: |...:|.|..:|....|...      ....|:
pombe   276 H--------------TKASDIVQIASGTEHNI-LRTKKGSVLIYGWNEHGNASNDDKRDVYDAKT 325

  Fly   348 LMLP 351
            |.||
pombe   326 LQLP 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Herc4	NP_001261249.1	RCC1	6..55	CDD:278826	17/43 (40%)
		RCC1	59..110	CDD:278826	17/60 (28%)
		RCC1	114..163	CDD:278826	12/64 (19%)
		RCC1	167..218	CDD:278826	15/56 (27%)
		RCC1	221..270	CDD:278826	9/62 (15%)
		RCC1	273..322	CDD:278826	12/48 (25%)
		RCC1_2	309..339	CDD:290274	9/29 (31%)
		RCC1	327..390	CDD:278826	8/31 (26%)
		HECTc	715..1060	CDD:238033
		HECTc	739..1059	CDD:214523
SPAC10F6.04	NP_001342701.1	ATS1	1..351	CDD:227511	95/394 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910