DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment sturkopf and ldah

DIOPT Version :9

Sequence 1:	NP_612097.1	Gene:	sturkopf / 38150	FlyBaseID:	FBgn0035206	Length:	307	Species:	Drosophila melanogaster
Sequence 2:	XP_002934536.2	Gene:	ldah / 779625	XenbaseID:	XB-GENE-985182	Length:	372	Species:	Xenopus tropicalis

Alignment Length:	315	Identity:	105/315 - (33%)
Similarity:	174/315 - (55%)	Gaps:	20/315 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQEAYVNINSIPTHIFTWGRW--IEETITE---KEIVICITGNPGLPGFYTEFAGTLQKELGD-L 59
            :.:.::..:...|.:..:|.|  ::::..|   |.:::.|.||||:.|||..|..:|...|.. .
Frog    62 VHDEFIYCSGGATEVLKFGPWKDLQKSNGESKPKLLILIIPGNPGVVGFYRTFMQSLYCSLDQRY 126

  Fly    60 PVWVIGHAGHDDPPEA--SIREVPQLSGNEELFNLDGQIRHKIAFIEKYVPSDVKIHLIGHSIGA 122
            |||.|.||||..||..  ..:|..|:   |::|.|:|||.||::|::::||:|:|:.|||||||.
Frog   127 PVWAISHAGHCSPPRGMDMTQEYDQM---EDVFGLNGQIEHKLSFMKEHVPADIKLILIGHSIGC 188

  Fly   123 WMILQLLENERIRSRIQKCYMLFPTVERMMESPNGWVFTKVAMPLYSVFGYIFFS---FFNFLPV 184
            ::||:::: .....::.:..|||||:|||.:||.|    |:..||.....|:|:.   ..:|||.
Frog   189 YIILEMMK-RAADLKVLQSIMLFPTIERMAQSPQG----KIMTPLLCSLRYVFYMPLYLLSFLPE 248

  Fly   185 WLRLMLIQIYFL-IFSIPRQFLGTALKYSKPSVAEKVVFLADDEMARVRGIQREIVEQNLDLLKF 248
            .|:..|::.... |.|:....:...|...:...|...:::...||.:|.......:::||..|.|
Frog   249 NLKTSLVRFVLRGIKSVDEASVEACLNLFRMDCAANAMYMGSQEMVKVLERDNNTIKRNLQKLIF 313

  Fly   249 YYGTTDGWVPISYYDQLKKDYPKVDAQLDTKKIDHAFVLRHSQPMAVIVRDMIQQ 303
            |||.||.|.|:.||:::||.:|:....|..|.|.|||||..|..:|.:..|.:::
Frog   314 YYGATDNWCPVQYYEEMKKAFPEGSILLCEKGIRHAFVLDSSNEVATMTIDWLKK 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
sturkopf	NP_612097.1	MhpC	4..304	CDD:223669	105/312 (34%)
sturkopf	NP_612097.1	DUF2305	28..286	CDD:287232	96/267 (36%)
ldah	XP_002934536.2	LIDHydrolase	94..351	CDD:370901	95/264 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	174	1.000	Domainoid score	I3643
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41453
Inparanoid	1	1.050	181	1.000	Inparanoid score	I3880
OMA	1	1.010	-	-		QHG53946
OrthoDB	1	1.010	-	-		D1163030at2759
OrthoFinder	1	1.000	-	-		FOG0004310
OrthoInspector	1	1.000	-	-		oto103098
Panther	1	1.100	-	-	LDO	PTHR13390
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4098
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.080