Sequence 1: | NP_001372213.1 | Gene: | KIT / 3815 | HGNCID: | 6342 | Length: | 977 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_524394.2 | Gene: | htl / 42160 | FlyBaseID: | FBgn0010389 | Length: | 729 | Species: | Drosophila melanogaster |
Alignment Length: | 754 | Identity: | 201/754 - (26%) |
---|---|---|---|
Similarity: | 318/754 - (42%) | Gaps: | 185/754 - (24%) |
- Green bases have known domain annotations that are detailed below.
Human 218 KASYLLR--EGEEFTVTC-TIKDVSSSVYSTWKRENSQQTKLQEKYNSWHHGDFNYERQA-TLTI 278
Human 279 SSARVNDSGVFMCYANNTFGSANVTTTLEVVDKGFINIFPMINTTVFVNDGENVDLIVEYEAFPK 343
Human 344 PEHQQWIYMNRTFTDKWEDYPKSENESNIRYVSELHLTRLKGTEGGTYTFLVSNSDVNAAIAFNV 408
Human 409 YVNTKPEILTYDRLVNGMLQCVAAGFPEPTIDWYFCPGTE---QRCSASVLPVDVQTLN--SSGP 468
Human 469 PFGKLVVQSSIDSSAFKH----NGTVECKAYNDVGKTSAYFNFAFKGNNKEQ--------IHPHT 521
Human 522 ----LFTPLLIGFVIVAGMMCIIVMILTYKYLQKPMYEVQWKVVEEI-NGNNYVYIDPTQLPYDH 581
Human 582 KWEFPRNRLSFGKTLGAGAFGKVVEATAYGLIKSDAAMTVAVKMLKPSAHLTEREALMSELKVLS 646
Human 647 YLGNHMNIVNLLGACTIGGPTLVITEYCCYGDLLNFLRRKRDSFICSKQEDHAEAALYKNLLHSK 711
Human 712 ESSCSDSTNEYMDMKPGVS---YVVPTKADKRRSVRIGSYIERDVTPAIMEDDELALDLEDLLSF 773
Human 774 SYQVAKGMAFLASKNCIHRDLAARNILLTHGRITKICDFGLARDIKNDSNYVVKGNARLPVKWMA 838
Human 839 PESIFNCVYTFESDVWSYGIFLWELFSLGSSPYPGMPVDSKFYKMIKEGFRMLSPEHAPAEMYDI 903
Human 904 MKTCWDADPLKRPTFKQIVQLIEKQISESTNHIYSNLAN 942 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KIT | NP_001372213.1 | Ig strand A | 212..215 | CDD:409353 | |
ig | 216..306 | CDD:395002 | 21/91 (23%) | ||
Ig strand B | 229..239 | CDD:409353 | 2/10 (20%) | ||
Ig strand C' | 250..252 | CDD:409353 | 0/1 (0%) | ||
Ig strand D | 260..263 | CDD:409353 | 0/2 (0%) | ||
Ig strand E | 267..280 | CDD:409353 | 4/13 (31%) | ||
Ig strand F | 287..294 | CDD:409353 | 2/6 (33%) | ||
Ig strand G | 300..308 | CDD:409353 | 1/7 (14%) | ||
IgI_4_SCFR | 312..412 | CDD:409446 | 13/99 (13%) | ||
Ig strand B | 332..336 | CDD:409446 | 1/3 (33%) | ||
Ig strand C | 346..350 | CDD:409446 | 0/3 (0%) | ||
Ig strand E | 376..380 | CDD:409446 | 2/3 (67%) | ||
Ig strand F | 390..395 | CDD:409446 | 1/4 (25%) | ||
Ig strand G | 403..406 | CDD:409446 | 0/2 (0%) | ||
Ig | 427..503 | CDD:409353 | 16/84 (19%) | ||
Ig strand C | 438..442 | CDD:409353 | 0/3 (0%) | ||
Ig strand E | 471..479 | CDD:409353 | 1/7 (14%) | ||
Ig strand F | 489..494 | CDD:409353 | 0/4 (0%) | ||
PTKc_Kit | 554..929 | CDD:270682 | 133/378 (35%) | ||
Important for interaction with phosphotyrosine-binding proteins | 569..571 | 0/1 (0%) | |||
htl | NP_524394.2 | Ig | 112..191 | CDD:299845 | 19/89 (21%) |
IG_like | 113..191 | CDD:214653 | 18/88 (20%) | ||
IG_like | 205..289 | CDD:214653 | 19/136 (14%) | ||
PKc_like | 404..692 | CDD:304357 | 129/353 (37%) | ||
STYKc | 416..688 | CDD:214568 | 122/337 (36%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG0200 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
2 | 1.810 |