Protein Alignment Nt5a and nt5dc1

DIOPT Version :10

• Sequence 1: NP_612095.3
• Gene: Nt5a / 38148
• FlyBaseID: FBgn0035204
• Length: 534
• Species: Drosophila melanogaster
• Sequence 2: NP_001098413.1
• Gene: nt5dc1 / 568757
• ZFINID: ZDB-GENE-030131-8274
• Length: 461
• Species: Danio rerio
• Alignment Length: 478
• Identity: 156/478 - (32%)
• Similarity: 234/478 - (48%)
• Gaps: 79/478 - (16%)

  Fly   100 MTSYHKELLLKDYGIVGFDLDGTLLRYNLHEMSALIYQVLKQFLVEQKGYDRDLL-LQSLNLDFL 163
            |:.|..   |.:..::|||||.||.||.|.|.|.|||:...::|||.||||:||| |.....||.
Zfish     1 MSEYFS---LSECDVIGFDLDHTLCRYYLKETSRLIYESFARYLVEHKGYDKDLLHLTPATWDFC 62

  Fly   164 QKGLFLDGPRGNVLKLSSEAQILRATHGTRLLSDTEIQAIYGRDRRWE----ITTAFYRDPLSTW 224
            .|||.:|...||::||:.:..:|||||||:.||..:|...||..|.|:    :.|::.|
Zfish    63 FKGLVVDLEEGNLVKLAEDGTVLRATHGTKNLSTDDIVKHYGPKREWKHFNSLNTSYTR------ 121

  Fly   225 NGDASTQMRSLLDYFDMPSALVFAQAVDLVDRGKKPSAGEEY--QVWQDVQAGLMNIYSRENFAN 287
                |.:.....:|||:|.||:.|:.||::::     .|.|.  ..|:|:.|.:.:.|:...|..
Zfish   122 ----SAKYYFYDNYFDLPGALLCARVVDMMNK-----QGTEITSDFWKDIVAAIDHNYNTSAFRE 177

  Fly   288 DQSLYFKSMRAEPERFVLRTDPSVMNWLGELRKSGKKLFLLTGSNVDFANLTATQALGKDWRKYF 352
            |...||.|::..|.|::.....:|..||..::.|||.|.|:|.|:.|:..|.....||.|:.:.|
Zfish   178 DTGTYFPSVKRCPGRYLQPCSDTVRRWLRSIKNSGKILLLITSSHSDYCRLVCEHILGSDFEELF 242

  Fly   353 DFVVTYAKKPGFFTM---QRPFMQV--DVEKLAELPQEADNIKAGEVYSQGNWHQLHTAMAGMLQ 412
            |.::|.|.|||||::   ||||..:  |||....||    :::....||||||..||..:..|..
Zfish   243 DVIITNALKPGFFSLVPQQRPFRTLVDDVEDSEGLP----SLEKPGWYSQGNWPHLHELLKTMTN 303

  Fly   413 KKPSEAKALYFGDNIIQDVYTPVKHRDFDAVAIAEELLLE------------------DGKYPYA 459
            |  :|.|.:||||::..|::.......::.|.|.||:..|                  :|.....
Zfish   304 K--AEPKVVYFGDSMRSDMFPACSFAKWETVMIVEEMEGEGVPRADGCPSNSSSGGPSEGPVEKK 366

  Fly   460 AELD----------SQLWGPYFALDCTPT--------LWSSF-ISSYAQLCVPTVEQVAQTAPD- 504
            |:.:          |:.||.|| :|...|        .|... |.:|:.:.:|::|.:|....|
Zfish   367 AKFEDQGMKSPSDSSKQWGSYF-VDVQKTEGEETQKLTWCCHSIHTYSTMAIPSIEAIADLPLDF 430

  Fly   505 --KRIVCHNPY--GFSPRLPKEL 523
              :|.....|.  |:.||.|..|
Zfish   431 KFQRFSSEKPITTGYYPRPPDSL 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Nt5a	NP_612095.3	HAD_cN-II	102..490	CDD:319824	144/436 (33%)
nt5dc1	NP_001098413.1	Haloacid Dehalogenase-like Hydrolases	7..341	CDD:473868	130/354 (37%)