Protein Alignment CG9149 and HADHB

DIOPT Version :9

• Sequence 1: NP_612094.2
• Gene: CG9149 / 38147
• FlyBaseID: FBgn0035203
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_000174.1
• Gene: HADHB / 3032
• HGNCID: 4803
• Length: 474
• Species: Homo sapiens
• Alignment Length: 429
• Identity: 133/429 - (31%)
• Similarity: 216/429 - (50%)
• Gaps: 53/429 - (12%)

  Fly     3 DVFIVSAARTPIGSFNGTLSK-LKASDLGSVVIQEVLRRANVEGQEVNEVILGQALSAGQGQNPA 66
            :|.:|...|||. ..:||..| |...||....:..:|.|.:|..:.|:.:|.|..:...:..|.|
Human    53 NVVVVDGVRTPF-LLSGTSYKDLMPHDLARAALTGLLHRTSVPKEVVDYIIFGTVIQEVKTSNVA 116

  Fly    67 RQASLKAGLPIQVPAYGINMLCGSGLKTVALGYQAIRSGDAQIVVAGGQESMSLAPHVMHLRQGV 131
            |:|:|.||...:.||:.:.|.|.|..:.:..|...|.||...::||||.|.||..| :.|.|:..
Human   117 REAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIASGQCDVIVAGGVELMSDVP-IRHSRKMR 180

  Fly   132 KMGPGTMVD-----------SMIH-----------DGLTDAMENIHMGITAENLADKYNISREAQ 174
            |:    |:|           |:|.           ..:::...:..||.:|:.||..:.:||..|
Human   181 KL----MLDLNKAKSMGQRLSLISKFRFNFLAPELPAVSEFSTSETMGHSADRLAAAFAVSRLEQ 241

  Fly   175 DAYAVLSQNRAEEAQKKGYFDKEIVPVEIKDRKGTTTFSKDEYIKAGSTVEGIQKLRAAF-KEGG 238
            |.||:.|.:.|::||.:|.. .::||.::   .|..|.:||..|:. |::|.:.||:.|| |..|
Human   242 DEYALRSHSLAKKAQDEGLL-SDVVPFKV---PGKDTVTKDNGIRP-SSLEQMAKLKPAFIKPYG 301

  Fly   239 SITAGNASGVNDSAAAVLLMSGEEVARKGLKPLARIVGWTQSGIEPK-VMGLGPVTAVEALLQKI 302
            ::||.|:|.:.|.|:|:|:|:.|:....|.||.|.:..:.....:|| .:.|||..|...:|:|.
Human   302 TVTAANSSFLTDGASAMLIMAEEKALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKA 366

  Fly   303 NWKREEVDLYELNEAFAAQSLAVLQDLQLD-----------------AQKVNVNGGAIALGHPIG 350
            .....::|.:|.:|||:.|.||..:.:..|                 .:|.|..||:::||||.|
Human   367 GLTMNDIDAFEFHEAFSGQILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFG 431

  Fly   351 ASGARVLVTLLYALERTGGRKGIASLCIGGGMGIALAVE 389
            |:|.|:::.....|.:.||:.|:.:.|..||.|.|:.||
Human   432 ATGCRLVMAAANRLRKEGGQYGLVAACAAGGQGHAMIVE 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9149	NP_612094.2	PRK05790	1..391	CDD:180261	133/429 (31%)
		thiolase	5..390	CDD:238383	132/427 (31%)
HADHB	NP_000174.1	thiolase	55..471	CDD:238383	132/427 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820