DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9149 and Acat2

DIOPT Version :9

Sequence 1:	NP_612094.2	Gene:	CG9149 / 38147	FlyBaseID:	FBgn0035203	Length:	392	Species:	Drosophila melanogaster
Sequence 2:	NP_033364.2	Gene:	Acat2 / 110460	MGIID:	87871	Length:	397	Species:	Mus musculus

Alignment Length:	389	Identity:	231/389 - (59%)
Similarity:	295/389 - (75%)	Gaps:	2/389 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VFIVSAARTPIGSFNGTLSKLKASDLGSVVIQEVLRRANVEGQEVNEVILGQALSAGQGQNPARQ 68
            |.|||||||.||||||.||.:...::|:.||:|||:||.|..:||:|||.|..|:||.||||.||
Mouse     8 VVIVSAARTAIGSFNGALSTVPVHEMGTTVIKEVLQRAKVAPEEVSEVIFGHVLTAGCGQNPTRQ 72

  Fly    69 ASLKAGLPIQVPAYGINMLCGSGLKTVALGYQAIRSGDAQIVVAGGQESMSLAPHVMHLRQGVKM 133
            ||:.||:|..|||:...|:||||||.|.|..|:|..||:.||||||.|:||.|||:.|||.||:|
Mouse    73 ASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHLTHLRTGVRM 137

  Fly   134 GPGTMVDSMIHDGLTDAMENIHMGITAENLADKYNISREAQDAYAVLSQNRAEEAQKKGYFDKEI 198
            |...:.||::.||||||..|.||||||||:|.|:.:||||||..|||||||||.|||.|:|||||
Mouse   138 GEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVLSQNRAEHAQKAGHFDKEI 202

  Fly   199 VPVEIKDRKGTTTFSKDEYIKAGSTVEGIQKLRAAF-KEG-GSITAGNASGVNDSAAAVLLMSGE 261
            |||.:..|||.|....||:.:.||.:|.:.||:..| .:| |::|..||||:||.||||:||...
Mouse   203 VPVLVSSRKGLTEVKIDEFPRHGSNLEAMGKLKPYFLTDGTGTVTPANASGMNDGAAAVVLMKKT 267

  Fly   262 EVARKGLKPLARIVGWTQSGIEPKVMGLGPVTAVEALLQKINWKREEVDLYELNEAFAAQSLAVL 326
            |..|:.||||||||.|:|:|:||.|||:||:.|::..:.|..|..|:|||:|:||||||.|.|:.
Mouse   268 EAERRMLKPLARIVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDLFEINEAFAAVSAAIA 332

  Fly   327 QDLQLDAQKVNVNGGAIALGHPIGASGARVLVTLLYALERTGGRKGIASLCIGGGMGIALAVER 390
            ::|.|:.:|||::|||||||||:||||.|:|||||:.|||.||.:|:|:||||||||:|:.|:|
Mouse   333 KELGLNPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGGTRGVAALCIGGGMGVAMCVQR 396

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9149	NP_612094.2	PRK05790	1..391	CDD:180261	231/389 (59%)
CG9149	NP_612094.2	thiolase	5..390	CDD:238383	229/386 (59%)
Acat2	NP_033364.2	PRK05790	8..396	CDD:180261	230/387 (59%)
Acat2	NP_033364.2	thiolase	9..396	CDD:238383	229/386 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836829
Domainoid	1	1.000	289	1.000	Domainoid score	I1550
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H55855
Inparanoid	1	1.050	458	1.000	Inparanoid score	I1563
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60894
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	1	1.000	-	-		otm43130
orthoMCL	1	0.900	-	-		OOG6_100472
Panther	1	1.100	-	-	LDO	PTHR18919
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R12059
SonicParanoid	1	1.000	-	-		X3780
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	16	15.800