Protein Alignment Acat2 and ACAA2

DIOPT Version :10

• Sequence 1: NP_612094.2
• Gene: Acat2 / 38147
• FlyBaseID: FBgn0035203
• Length: 392
• Species: Drosophila melanogaster
• Sequence 2: NP_006102.2
• Gene: ACAA2 / 10449
• HGNCID: 83
• Length: 397
• Species: Homo sapiens
• Alignment Length: 388
• Identity: 173/388 - (44%)
• Similarity: 243/388 - (62%)
• Gaps: 2/388 - (0%)

  Fly     4 VFIVSAARTPIGSFNGTLSKLKASDLGSVVIQEVLRRANVEGQEVNEVILGQAL-SAGQGQNPAR 67
            ||:|:|.|||.|::.|.|....|:||.....:..|....|..:.|:.||:|..| |:......||
Human     7 VFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSSDAIYLAR 71

  Fly    68 QASLKAGLPIQVPAYGINMLCGSGLKTVALGYQAIRSGDAQIVVAGGQESMSLAPH-VMHLRQGV 131
            ...|:.|:|.:.||..||.|||||.:::..|.|.|...:|::|:.||.||||.||: |.::|.|.
Human    72 HVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVRNVRFGT 136

  Fly   132 KMGPGTMVDSMIHDGLTDAMENIHMGITAENLADKYNISREAQDAYAVLSQNRAEEAQKKGYFDK 196
            |:|....::..:...|||....:.|.:||||||.|:.||||..|.||:.||.|.:.|...|||:.
Human   137 KLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAANDAGYFND 201

  Fly   197 EIVPVEIKDRKGTTTFSKDEYIKAGSTVEGIQKLRAAFKEGGSITAGNASGVNDSAAAVLLMSGE 261
            |:.|:|:|.:||..|...||:.:..:|:|.:|||...||:.|::||||||||.|.|.||::.|.:
Human   202 EMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAVIIASED 266

  Fly   262 EVARKGLKPLARIVGWTQSGIEPKVMGLGPVTAVEALLQKINWKREEVDLYELNEAFAAQSLAVL 326
            .|.:....|||||||:..||.:|.:||:|||.|:...|:|.....:::||.|:|||||.|.|||.
Human   267 AVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAPQYLAVE 331

  Fly   327 QDLQLDAQKVNVNGGAIALGHPIGASGARVLVTLLYALERTGGRKGIASLCIGGGMGIALAVE 389
            :.|.||..|.||||||||||||:|.||:|:...|::.|.|.||:..:.|.|||||.|||:.::
Human   332 RSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 394

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Acat2	NP_612094.2	PRK05790	1..391	CDD:180261	173/388 (45%)
ACAA2	NP_006102.2	thiolase	8..394	CDD:238383	172/385 (45%)