DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rac1 and Rhoh

DIOPT Version :9

Sequence 1:NP_001261247.1 Gene:Rac1 / 38146 FlyBaseID:FBgn0010333 Length:192 Species:Drosophila melanogaster
Sequence 2:NP_001074574.1 Gene:Rhoh / 74734 MGIID:1921984 Length:191 Species:Mus musculus


Alignment Length:177 Identity:75/177 - (42%)
Similarity:117/177 - (66%) Gaps:7/177 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65
            :.:||||:|||.|||||.||:.:|:..||..|.|||::|...:|.:|...|:||||||||.:.:.
Mouse     2 LSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTAGNDAFR 66

  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLR 130
            .:|||||.|.||.|:|:|:.|..||.|::.||..|:|.:.|.||:::|.|:.|.|:       :.
Mouse    67 SIRPLSYQQADVVLMCYSVANHNSFLNLKNKWISEIRSNLPCTPVLVVATQTDQRE-------VG 124

  Fly   131 DKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVL 177
            ..:.:.|...:|..:|:::.|..|||||||:.:|::.||:.|:|:.:
Mouse   125 PHRASCINAIEGKRLAQDVRAKGYLECSALSNRGVQQVFECAVRTAV 171

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rac1NP_001261247.1 Rac1_like 3..176 CDD:206663 75/172 (44%)
RhohNP_001074574.1 Rho 5..169 CDD:206641 74/170 (44%)
Effector region. /evidence=ECO:0000250 33..41 4/7 (57%)
Interaction with ZAP70. /evidence=ECO:0000269|PubMed:17028588 73..86 7/12 (58%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1091615at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24072
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.920

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