DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Rac1 and rhobtb2b

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	XP_017213602.2	Gene:	rhobtb2b / 565844	ZFINID:	ZDB-GENE-071125-1	Length:	722	Species:	Danio rerio

Alignment Length:	229	Identity:	84/229 - (36%)
Similarity:	117/229 - (51%)	Gaps:	48/229 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49
            ::.||||||||.|||||.|:.:...||...:|      :|||:  |.|        .:..:||..
Zfish    23 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 87

  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVG 114
            .::|.||||.|  |:.:.|..:|.::||.::|||:.||.|..:|:..||||::|.||..|:||||
Zfish    88 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLFHVKTMWYPEIKHFCPRAPVILVG 150

  Fly   115 TKLDLR-DDKNTIEKLRDKKLAPITY------PQGLAMAKEIGAVKYLECSALTQKGLKTVFDEA 172
            .:|||| .|...:.:.|.....||..      .:|..:|||: .|.|.|.|.:.|.|:|.|||.|
Zfish   151 CQLDLRYADLEAVNRARRPLARPIKANEILPPEKGREVAKEL-CVPYYETSVVAQFGVKDVFDNA 214

  Fly   173 IRSVL----------------------CPVLQPK 184
            ||:.|                      .|.|.||
Zfish   215 IRAALISRRHLQFWKSHLRDVQRPLLQAPFLPPK 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	79/195 (41%)
rhobtb2b	XP_017213602.2	RhoBTB	24..218	CDD:133275	79/196 (40%)
		BTB	270..>310	CDD:321966
		BTB	<412..456	CDD:333434
		BTB	487..579	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810