DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and rhobtb4

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001352487.1	Gene:	rhobtb4 / 553415	ZFINID:	ZDB-GENE-060315-11	Length:	729	Species:	Danio rerio

Alignment Length:	232	Identity:	89/232 - (38%)
Similarity:	122/232 - (52%)	Gaps:	48/232 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEY------IPTVF--DNY--------SANVMVDAK 49
            ::.||||||||.|||||.|:.:...||...:|      :|||:  |.|        .:..:||..
Zfish    25 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEV 89

  Fly    50 PINLGLWDTAGQEDYDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVG 114
            .::|.||||.|  |:.:.|..:|.::||.::||||.||.|..:||..|:||::|.||.|||||||
Zfish    90 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSLANPNSLRHVRTMWFPEIKHFCPRTPIILVG 152

  Fly   115 TKLDLR-DDKNTIEKLRDKKLAPI----TYP--QGLAMAKEIGAVKYLECSALTQKGLKTVFDEA 172
            .:|||| .|.:.:.:.|.....||    ..|  :|..:|||:| |.|.|.|.:.|.|:|.|||.|
Zfish   153 CQLDLRYADLDAVNRARRPLAKPIKPTDILPPERGHEVAKELG-VPYYETSIVAQFGVKDVFDNA 216

  Fly   173 IRSVL----------------------CPVLQPKSKR 187
            ||:.|                      .|.|.|:..|
Zfish   217 IRAALISRRHLQFWKSHLKKVQRPLLQAPFLPPRPPR 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	84/195 (43%)
rhobtb4	NP_001352487.1	RhoBTB	26..220	CDD:133275	84/196 (43%)
		BTB	<426..486	CDD:333434
		BTB	505..612	CDD:306997
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810