DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and rhoh

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001314902.1	Gene:	rhoh / 553413	ZFINID:	ZDB-GENE-060228-7	Length:	195	Species:	Danio rerio

Alignment Length:	180	Identity:	78/180 - (43%)
Similarity:	117/180 - (65%)	Gaps:	17/180 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYDRL 67
            ::|||:|||.|||||.||:.:|:..||..|.|||::|...:|.:|...|:||||||||.:.:.::
Zfish     8 SVKCVLVGDCAVGKTALLVRFTSETFPDSYRPTVYENTGVDVFMDGIQISLGLWDTAGHDTFRQI 72

  Fly    68 RPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLRDK 132
            ||:||..|||.|:|:|:.||:|..|:|.||..|||.:.|..|:::|.|:.|.|:
Zfish    73 RPMSYQDTDVVLLCYSVANPSSLNNLRHKWIAEVREYLPKVPVLVVATQTDHRE----------- 126

  Fly   133 KLAP-----ITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVL 177
             :.|     .|.|:|..:|:||.|..|||||||:.:|::.||:.|:|:.:
Zfish   127 -MGPYRANCTTSPEGKQVAQEIRAKGYLECSALSNRGVQQVFECAVRTAV 175

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	78/177 (44%)
rhoh	NP_001314902.1	Rho	9..173	CDD:206641	77/175 (44%)
rhoh	NP_001314902.1	RHO	11..176	CDD:197554	77/177 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24072
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920