DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and Miro

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001262895.1	Gene:	Miro / 42845	FlyBaseID:	FBgn0039140	Length:	673	Species:	Drosophila melanogaster

Alignment Length:	201	Identity:	53/201 - (26%)
Similarity:	86/201 - (42%)	Gaps:	42/201 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFD-NYSANVMVDAKPINLGLWDTAGQEDYDRL 67
            ::.::|||..||||.|::|..:..:|.|..|...: ...|||..:..|.:  :.|.:..|..:..
  Fly    12 VRILLVGDAGVGKTSLILSLVSEEYPEEVPPRAEEITIPANVTPEQVPTS--IVDFSAVEQSEDA 74

  Fly    68 RPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHC-PS---------------------TPI 110
            ......:..|..|.:::.:..:.:.:.:.|.|.||..| ||                     .||
  Fly    75 LAAEINKAHVVCIVYAVDDDDTLDRITSHWLPLVRAKCNPSLDGEGDAEAEAEGDTQREPIRKPI 139

  Fly   111 ILVGTKLDLRDDKNTIE-KLRDKKLAPI-TYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAI 173
            :|||.|:||      || ...|..||.: .||       ||.:.  :||||.:...:..:|..|.
  Fly   140 VLVGNKIDL------IEYSTMDSVLAIMEDYP-------EIESC--VECSAKSLHNISEMFYYAQ 189

  Fly   174 RSVLCP 179
            ::||.|
  Fly   190 KAVLHP 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	50/196 (26%)
Miro	NP_001262895.1	Miro1	10..195	CDD:206680	52/199 (26%)
		RHO	14..195	CDD:197554	52/197 (26%)
		EF_assoc_2	247..328	CDD:285547
		EF_assoc_1	367..437	CDD:285546
		Miro2	444..620	CDD:206679
		Ras	448..602	CDD:278499
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24072
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030