DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rac1 and RHOA

DIOPT Version :9

Sequence 1:NP_001261247.1 Gene:Rac1 / 38146 FlyBaseID:FBgn0010333 Length:192 Species:Drosophila melanogaster
Sequence 2:NP_001300870.1 Gene:RHOA / 387 HGNCID:667 Length:193 Species:Homo sapiens


Alignment Length:194 Identity:106/194 - (54%)
Similarity:135/194 - (69%) Gaps:3/194 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQED 63
            |.||  |.|:|||||.|||||||.::.:.||..|:||||:||.|::.||.|.:.|.|||||||||
Human     1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65

  Fly    64 YDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEK 128
            ||||||||||.|||.|:|||:.:|.|.||:..||.|||:|.||:.||||||.|.|||:|::|..:
Human    66 YDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRE 130

  Fly   129 LRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192
            |...|..|:...:|..||..|||..|:||||.|:.|::.||:.|.|:.| ...:.|.|..|.:|
Human   131 LAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAAL-QARRGKKKSGCLVL 193

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rac1NP_001261247.1 Rac1_like 3..176 CDD:206663 100/174 (57%)
RHOANP_001300870.1 RhoA_like 5..179 CDD:206662 98/173 (57%)
Effector region. /evidence=ECO:0000255 34..42 5/7 (71%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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