DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and rac1a

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_956065.1	Gene:	rac1a / 327204	ZFINID:	ZDB-GENE-030131-5415	Length:	192	Species:	Danio rerio

Alignment Length:	192	Identity:	173/192 - (90%)
Similarity:	184/192 - (95%)	Gaps:	0/192 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65
            |||||||||||||||||||||||||||||||||||||||||||||||.||:||||||||||||||
Zfish     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYD 65

  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLR 130
            ||||||||||||||||||||:||||||||||||||||||||:||||||||||||||||:|||||:
Zfish    66 RLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPNTPIILVGTKLDLRDDKDTIEKLK 130

  Fly   131 DKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCALL 192
            :|||.|||||||||||||||||||||||||||:|||||||||||:||||....:.:|:|.||
Zfish   131 EKKLTPITYPQGLAMAKEIGAVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKRRRRRCLLL 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	163/172 (95%)
rac1a	NP_956065.1	Rac1_like	3..176	CDD:206663	163/172 (95%)
rac1a	NP_956065.1	RHO	6..179	CDD:197554	162/172 (94%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	344	1.000	Domainoid score	I1028
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69035
Inparanoid	1	1.050	364	1.000	Inparanoid score	I2132
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	1	1.000	-	-		mtm6376
orthoMCL	1	0.900	-	-		OOG6_100633
Panther	1	1.100	-	-	LDO	PTHR24072
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2743
SonicParanoid	1	1.000	-	-		X103
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.860