DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and RSA-14-44

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_872611.2	Gene:	RSA-14-44 / 297173	RGDID:	735071	Length:	193	Species:	Rattus norvegicus

Alignment Length:	191	Identity:	109/191 - (57%)
Similarity:	138/191 - (72%)	Gaps:	3/191 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAI--KCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQED 63
            |.||  |.|:|||||.|||||||.::.:.||..|:||||:||.|::.||.|.:.|.|||||||||
  Rat     1 MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPDVYVPTVFENYVADIEVDGKQVELALWDTAGQED 65

  Fly    64 YDRLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEK 128
            ||||||||||.|||.|||||:.||.||.|:..||.|||:|.||:.||||||:|.|||:|.|||::
  Rat    66 YDRLRPLSYPDTDVLLICFSIGNPDSFGNIPHKWIPEVKHFCPNVPIILVGSKKDLRNDLNTIQE 130

  Fly   129 LRDKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKC 189
            |..:|..|:...||..:|..|||.:|:||||.|:.|::.||::|.|:.| ...:.|.|..|
  Rat   131 LAKRKQEPVKPEQGRDLANSIGAFEYVECSAKTKDGVRKVFEKATRAAL-QTNRVKKKTGC 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	104/174 (60%)
RSA-14-44	NP_872611.2	RhoA_like	5..179	CDD:206662	102/173 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810