DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rac1 and Rac3

DIOPT Version :9

Sequence 1:	NP_001261247.1	Gene:	Rac1 / 38146	FlyBaseID:	FBgn0010333	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_573486.1	Gene:	Rac3 / 170758	MGIID:	2180784	Length:	192	Species:	Mus musculus

Alignment Length:	191	Identity:	171/191 - (89%)
Similarity:	182/191 - (95%)	Gaps:	0/191 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDAKPINLGLWDTAGQEDYD 65
            |||||||||||||||||||||||||||||||||||||||||||||||.||:||||||||||||||
Mouse     1 MQAIKCVVVGDGAVGKTCLLISYTTNAFPGEYIPTVFDNYSANVMVDGKPVNLGLWDTAGQEDYD 65

  Fly    66 RLRPLSYPQTDVFLICFSLVNPASFENVRAKWYPEVRHHCPSTPIILVGTKLDLRDDKNTIEKLR 130
            ||||||||||||||||||||:||||||||||||||||||||.|||:||||||||||||:|||:||
Mouse    66 RLRPLSYPQTDVFLICFSLVSPASFENVRAKWYPEVRHHCPHTPILLVGTKLDLRDDKDTIERLR 130

  Fly   131 DKKLAPITYPQGLAMAKEIGAVKYLECSALTQKGLKTVFDEAIRSVLCPVLQPKSKRKCAL 191
            ||||||||||||||||:|||:|||||||||||:|||||||||||:||||....|..:||.:
Mouse   131 DKKLAPITYPQGLAMAREIGSVKYLECSALTQRGLKTVFDEAIRAVLCPPPVKKPGKKCTV 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rac1	NP_001261247.1	Rac1_like	3..176	CDD:206663	162/172 (94%)
Rac3	NP_573486.1	Rac1_like	3..176	CDD:206663	162/172 (94%)
Rac3	NP_573486.1	Effector region. /evidence=ECO:0000255	32..40		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	342	1.000	Domainoid score	I1070
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	366	1.000	Inparanoid score	I2142
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100633
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X103
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.730