Protein Alignment scf and CALU

DIOPT Version :10

• Sequence 1: NP_477392.1
• Gene: scf / 38145
• FlyBaseID: FBgn0025682
• Length: 329
• Species: Drosophila melanogaster
• Sequence 2: NP_001186600.1
• Gene: CALU / 813
• HGNCID: 1458
• Length: 323
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 161/327 - (49%)
• Similarity: 224/327 - (68%)
• Gaps: 17/327 - (5%)

  Fly     6 IQMLLLVVALTAVISGASASSIPEELPHNPLEHDPLH--PRHFDGGEHNAQFDHEAFLGPDESKK 68
            ::..|:.::|....:.:..:...:.:.|.|...|.:|  .:.||       :||:||||.:|:|.
Human    11 LRQFLMCLSLCTAFALSKPTEKKDRVHHEPQLSDKVHNDAQSFD-------YDHDAFLGAEEAKT 68

  Fly    69 FDSLTPEESRRRLGVIVDRIDENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQHNPDNNETIS 133
            ||.||||||:.|||.||.:||.:|||.||:.|||:||.:.|:|:|.|||.|.||.|:.:.:..:|
Human    69 FDQLTPEESKERLGKIVSKIDGDKDGFVTVDELKDWIKFAQKRWIYEDVERQWKGHDLNEDGLVS 133

  Fly   134 WDSYMQTVYGF-MDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQDLDDNLTKDEFTAFLHPED 197
            |:.|....||: :||..||:      |.:||.::.||..|:.:||:|.|...||:|||||||||:
Human   134 WEEYKNATYGYVLDDPDPDD------GFNYKQMMVRDERRFKMADKDGDLIATKEEFTAFLHPEE 192

  Fly   198 HPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAEDEEPEWVANEREAFSTHRDLDKDGY 262
            :..||.:|::||:.|:||:.||.|.::|||||||...|..| |||||..|||.|...||.::||.
Human   193 YDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTD-EPEWVKTEREQFVEFRDKNRDGK 256

  Fly   263 LNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQATDFGEALARHD 327
            :::||.|.||.|.|:||:||||:||::|:|.:.|.|||||||:||||:|||||||||||||.|||
Human   257 MDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQATDFGEALVRHD 321

  Fly   328 EF 329
            ||
Human   322 EF 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
scf	NP_477392.1	EFh_CREC_Calumenin_like	45..313	CDD:320024	138/268 (51%)
		EF-hand motif	45..74	CDD:320024	13/28 (46%)
		EF-hand motif	80..109	CDD:320024	17/28 (61%)
		EF-hand motif	116..145	CDD:320024	11/29 (38%)
		EF-hand motif	168..197	CDD:320024	17/28 (61%)
		EF-hand motif	205..234	CDD:320024	16/28 (57%)
		EF-hand motif	247..276	CDD:320024	14/28 (50%)
		EF-hand motif	283..313	CDD:320024	19/29 (66%)
CALU	NP_001186600.1	EFh_CREC_Calumenin	45..307	CDD:320026	139/275 (51%)
		EF-hand motif	45..74	CDD:320026	14/35 (40%)
		EF-hand motif	80..109	CDD:320026	17/28 (61%)
		EF-hand motif	116..145	CDD:320026	11/28 (39%)
		EF-hand motif	163..192	CDD:320026	17/28 (61%)
		EF-hand motif	200..229	CDD:320026	16/28 (57%)
		EF-hand motif	241..270	CDD:320026	14/28 (50%)
		EF-hand motif	277..307	CDD:320026	19/29 (66%)