DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment scf and rcn2

DIOPT Version :9

Sequence 1:	NP_477392.1	Gene:	scf / 38145	FlyBaseID:	FBgn0025682	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001116488.1	Gene:	rcn2 / 733807	XenbaseID:	XB-GENE-5917368	Length:	313	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	109/298 - (36%)
Similarity:	169/298 - (56%)	Gaps:	8/298 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LEHDPLHPRHFDGGEHNAQFDHEAFL-GPDESKKFDSLTPEESRRRLGVIVDRIDENKDGSVTLA 99
            |.|.  |..|::.|||||:||.:.|| |.:|:::|..|:||:..:||..|:.:||.:.||.:|..
Frog    18 LAHQ--HEEHYENGEHNAEFDKKMFLGGEEEAEEFTELSPEDQLKRLKSIIRKIDTDSDGYLTEE 80

  Fly   100 ELKNWIAYTQRRYIEEDVGRVWKQHNPDNNETISWDSYMQTVYGFMDDLSPDEKEQEENGVSYKS 164
            ||..||..:.:.||.||....:.:.:.|.:..::||.|...:|..:.|...:...::|...|::.
Frog    81 ELSFWIQKSFKHYILEDTKEHFAEIDKDGDGIVTWDEYNMHMYDRIIDYDENTVLEDEEEESFRQ 145

  Fly   165 LLKRDRYRWSVADQDLDDNLTKDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYIGD 229
            :..||:.|:..||:|....|...|||.|.|||:...|...|:...:.:.|||.||.:|::||:||
Frog   146 IHLRDKRRFDHADRDDIPGLNLTEFTDFEHPEETDHMSEFVIEGALEEHDKDGDGFVSLEEYLGD 210

  Fly   230 MYRSTGAEDEEPEWVANEREAFSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADAD 294
            ..:..|.. |:|.|:..|::.|....|.|.||.||..|:..||.|::...|:.||.||:.|.|.:
Frog   211 YTQDPGTV-EDPHWLIVEKDRFMNDYDKDGDGRLNPVELLSWIVPNNLGISQEEASHLMEEMDKN 274

  Fly   295 HDDKLTKEEILDKYDVFVGSQATDFGEALA----RHDE 328
            .|.:|::||||...|:|:.|:|||:|..|.    .|||
Frog   275 EDQRLSEEEILQNKDIFLTSEATDYGRQLQDKHFYHDE 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scf	NP_477392.1	EF-hand_7	170..227	CDD:290234	21/56 (38%)
		EFh	206..273	CDD:238008	24/66 (36%)
		EF-hand_7	248..308	CDD:290234	24/59 (41%)
		EFh	248..306	CDD:298682	23/57 (40%)
rcn2	NP_001116488.1	EFh_CREC_RCN2	25..292	CDD:320022	96/267 (36%)
		EF-hand motif	25..55	CDD:320022	14/29 (48%)
		EF-hand motif	61..90	CDD:320022	12/28 (43%)
		EF-hand motif	97..126	CDD:320022	6/28 (21%)
		EF-hand motif	149..178	CDD:320022	13/28 (46%)
		EF-hand motif	186..215	CDD:320022	11/28 (39%)
		EF-hand motif	227..256	CDD:320022	12/28 (43%)
		EF-hand motif	263..292	CDD:320022	13/28 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10827
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.110