DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scf and calua

DIOPT Version :9

Sequence 1:	NP_477392.1	Gene:	scf / 38145	FlyBaseID:	FBgn0025682	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001002151.2	Gene:	calua / 415241	ZFINID:	ZDB-GENE-040625-166	Length:	317	Species:	Danio rerio

Alignment Length:	331	Identity:	171/331 - (51%)
Similarity:	226/331 - (68%)	Gaps:	19/331 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RTRIQMLLLVVALTAVISGASASSIPEELPHNPLEHD-PLHPRHFDGGEHNAQFDHEAFLGPDES 66
            :..|:.||:..||..|.    |:|.|.| ..:.:.|| ||..:..|.|. |.::||:||||.:|:
Zfish     2 KMEIRPLLMCFALCVVY----ATSKPTE-KKDRVHHDAPLSSKEHDDGT-NFEYDHDAFLGEEEA 60

  Fly    67 KKFDSLTPEESRRRLGVIVDRIDENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQHNPDNNET 131
            |.||.||||||:.|||.||::||.::||.||.||||.||...|::||.::|.|.||..:.:|:..
Zfish    61 KTFDDLTPEESKNRLGKIVEKIDADEDGFVTEAELKAWIKKAQKKYIYDNVERQWKDFDLNNDRM 125

  Fly   132 ISWDSYMQTVYG-FMDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQDLDDNLTKDEFTAFLHP 195
            |||:.|....|| ::||..||:      |.:||.::.||..|:.:||.:.|....|:||||||||
Zfish   126 ISWEEYKNVTYGTYLDDPEPDD------GYNYKQMMARDERRFKMADGNGDHIADKEEFTAFLHP 184

  Fly   196 EDHPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAEDE--EPEWVANEREAFSTHRDLD 258
            |::..||.:|:.||:.|:||:.||.|.::|||||||..   |||  ||||||.|||.||..||.:
Zfish   185 EEYEHMKDIVVLETMEDIDKNGDGFIDLEEYIGDMYNH---EDEMDEPEWVATEREQFSEFRDKN 246

  Fly   259 KDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQATDFGEAL 323
            |||.::.||...||.|.|:||:|||||||::|:|.:.|.||||||||:|||:|||||||||||||
Zfish   247 KDGKMDREETMDWILPADYDHAEAEAKHLVYESDTNKDGKLTKEEILNKYDLFVGSQATDFGEAL 311

  Fly   324 ARHDEF 329
            .|||||
Zfish   312 VRHDEF 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scf	NP_477392.1	EF-hand_7	170..227	CDD:290234	26/56 (46%)
		EFh	206..273	CDD:238008	37/68 (54%)
		EF-hand_7	248..308	CDD:290234	35/59 (59%)
		EFh	248..306	CDD:298682	34/57 (60%)
calua	NP_001002151.2	EF-hand_7	75..132	CDD:290234	27/56 (48%)
		EF-hand_7	159..216	CDD:290234	26/56 (46%)
		EFh	159..216	CDD:298682	26/56 (46%)
		EFh	200..260	CDD:238008	34/62 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	93	1.000	Domainoid score	I7507
eggNOG	1	0.900	-	-		E1_KOG4223
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H936
Inparanoid	1	1.050	327	1.000	Inparanoid score	I2449
OMA	1	1.010	-	-		QHG48619
OrthoDB	1	1.010	-	-		D372250at33208
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	1	1.000	-	-		otm26091
orthoMCL	1	0.900	-	-		OOG6_105526
Panther	1	1.100	-	-	O	PTHR10827
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3115
SonicParanoid	1	1.000	-	-		X1088
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.870