DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment scf and CG31650

DIOPT Version :9

Sequence 1:	NP_477392.1	Gene:	scf / 38145	FlyBaseID:	FBgn0025682	Length:	329	Species:	Drosophila melanogaster
Sequence 2:	NP_001162879.1	Gene:	CG31650 / 326150	FlyBaseID:	FBgn0031673	Length:	342	Species:	Drosophila melanogaster

Alignment Length:	333	Identity:	124/333 - (37%)
Similarity:	189/333 - (56%)	Gaps:	23/333 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IQMLLLVVALTAVIS-----GASASSIPEE--LPHNPLEHDPLHPR----HFDGGEHNAQFDHEA 59
            :.:.|..|||.|.:.     ||.|:|...|  |....::.....||    |.:.||||.:|||||
  Fly     8 LPLTLCAVALLAAVGPMPAHGAVANSHKHEKHLSKERVKDGIYAPRDAHHHGEDGEHNVEFDHEA 72

  Fly    60 FLG-PDESKKFDSLTPEESRRRLGVIVDRIDENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQ 123
            .:| ..|:::||||:|:||:|||.:::..:|.|||..:...|||.||..:.::..||:....:::
  Fly    73 IIGNTKEAQEFDSLSPDESKRRLLILIKMMDLNKDEFIDRHELKAWILRSFKKLSEEEAADRFEE 137

  Fly   124 HNPDNNETISWDSYMQTVYGFMDDLSPDEKEQEENGVSY---KSLLKRDRYRWSVADQDLDDNLT 185
            .:.|.:|.|:|..|:|..|...|:   |.|::..:..||   :.::|:|:..::.||.:.|..||
  Fly   138 IDQDADERITWKEYLQDTYAMEDE---DFKKETIDYDSYEDEQKMIKQDKEMFNAADTNKDGVLT 199

  Fly   186 KDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYIGDMYRSTGAEDEEPEWVANEREA 250
            .:||..|.:||:||.|..::|..|:.|.|.||||||:..|::||     .|...:.||:..|:|.
  Fly   200 LEEFVLFQNPEEHPQMLPILLEHTMQDKDADHDGKINFQEFVGD-----AASHHDKEWLITEKER 259

  Fly   251 FSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEEILDKYDVFVGSQ 315
            |....|.:.||.|..:||..||.|.:...:..|..||....|.||||:|:..|||:.||.||||:
  Fly   260 FDKDHDSNGDGVLTGDEVLSWIVPSNTAIANDEVDHLFVSTDEDHDDRLSYLEILNNYDTFVGSE 324

  Fly   316 ATDFGEAL 323
            |||:|:.|
  Fly   325 ATDYGDHL 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
scf	NP_477392.1	EF-hand_7	170..227	CDD:290234	24/56 (43%)
		EFh	206..273	CDD:238008	26/66 (39%)
		EF-hand_7	248..308	CDD:290234	23/59 (39%)
		EFh	248..306	CDD:298682	22/57 (39%)
CG31650	NP_001162879.1	EF-hand_7	100..153	CDD:290234	16/52 (31%)
		EFh	100..153	CDD:298682	16/52 (31%)
		EF-hand_7	184..241	CDD:290234	24/56 (43%)
		EFh	184..241	CDD:298682	24/56 (43%)
		EFh	228..281	CDD:298682	22/57 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449116
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4223
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	83	1.000	Inparanoid score	I2353
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35792at33392
OrthoFinder	1	1.000	-	-		FOG0000638
OrthoInspector	1	1.000	-	-		mtm1075
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR10827
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.900