DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rabex-5 and VPS9B

DIOPT Version :9

Sequence 1:	NP_612093.1	Gene:	Rabex-5 / 38144	FlyBaseID:	FBgn0262937	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	NP_196494.2	Gene:	VPS9B / 830791	AraportID:	AT5G09320	Length:	437	Species:	Arabidopsis thaliana

Alignment Length:	412	Identity:	118/412 - (28%)
Similarity:	183/412 - (44%)	Gaps:	81/412 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 DLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYFTTDEDSDVKVQKR 244
            |.||:.:.|:.......|.:...::::.|:|.|..||.|||:    ||...|.::.:..:..:|.
plant    45 DAVQDFFYKMESAFRAHPLWSGCSDDELDNAGDGLEKYVMTK----LFPRVFASNTEDVISDEKL 105

  Fly   245 IRQLS----WITAKHLDCSIDEVNSEARDLVYNAISELVGIDSYYSPQEKLQCTWRCCRHIFELL 305
            .:::|    :|:.::||......|..:..|   |..||..|:.|.:|::||.|..|||:.|..||
plant   106 FQKISLVQQFISPENLDIQPTFQNQTSWLL---AQKELQKINMYNAPRDKLMCILRCCKVINNLL 167

  Fly   306 KRAT----GGPASADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRLMSGESGYYFTNLCSAI 366
            ..|:    .....||.|||.||:|.:||||.:.|||:.::.|:...|:|: ||:||.|||:.||.
plant   168 LNASIASNQNEPGADQFLPVLIYVTIKANPPQFHSNLLYIQRYRRQSKLV-GEAGYLFTNILSAE 231

  Fly   367 AFIENLNGESLGVSSEEFEALMS---------GQQPYSTPWESALLACESLHLISENMKRMEMLQ 422
            :||.|::.:||.:...:||..|.         |.|.|.|...:||..       :.|.||..||
plant   232 SFISNIDAKSLSMDEADFETKMKSAHARLSGPGSQSYQTDHGAALPT-------AHNTKRENML- 288

  Fly   423 KRNALISSGITSFE--KELIDFQREVTERVDTVIAKA-PLNLLPIKTPAFL-------------- 470
                |.:....||.  .|.:.         :|.|.|| |:..|..|..|.|
plant   289 ----LHTKSTDSFSGTNETLS---------ETPIKKADPITDLENKGAATLLNDRSEATKIFQEY 340

  Fly   471 ------IGQAR----AHLLNESEAGHYQANMLHGGSLTSQSLTAAGGLVKPAAASKESGLSLKDT 525
                  :|..:    ..|||..:...::...|..|...:.|||..   :.|..|||   :|...|
plant   341 PYMFASVGDLKIGDVEDLLNNYKQLVFKYVCLSKGLGDATSLTPC---ISPLQASK---VSENHT 399

  Fly   526 SMSSMGRLSPLQQNVQPADHLF 547
            ::||  ......:..:..|:||
plant   400 TLSS--DFQTKSETDRSVDNLF 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rabex-5	NP_612093.1	zf-A20	17..40	CDD:280010
Rabex-5	NP_612093.1	VPS9	274..373	CDD:280383	46/102 (45%)
VPS9B	NP_196494.2	DUF5601	24..88	CDD:407982	13/46 (28%)
VPS9B	NP_196494.2	VPS9	133..238	CDD:366977	47/108 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	87	1.000	Domainoid score	I2750
eggNOG	1	0.900	-	-		E2759_KOG2319
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944088at2759
OrthoFinder	1	1.000	-	-		FOG0002652
OrthoInspector	1	1.000	-	-		otm2483
orthoMCL	1	0.900	-	-		OOG6_102142
Panther	1	1.100	-	-	O	PTHR23101
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2025
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.820