DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rabex-5 and Ankrd27

DIOPT Version :10

Sequence 1:NP_612093.1 Gene:Rabex-5 / 38144 FlyBaseID:FBgn0262937 Length:696 Species:Drosophila melanogaster
Sequence 2:NP_001258193.1 Gene:Ankrd27 / 361555 RGDID:1307106 Length:1053 Species:Rattus norvegicus


Alignment Length:570 Identity:121/570 - (21%)
Similarity:206/570 - (36%) Gaps:147/570 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   173 KNINELSDLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYF----TT 233
            |::..|.|.|...|||....:..|...::...:  ::.::..::.|....|..::...|    |.
  Rat   169 KSLRHLIDSVNALYTKCLQQLLRDSHLKVLAKQ--EAQMNLMKQAVEMYVHHDIYDLIFKYVGTM 231

  Fly   234 DEDSDVKVQKRIRQLSWITAKHLDCSIDEVNSEARDLVYNAISELVGIDSYYSPQEKLQCTWRCC 298
            :...|....|..|.|..:..|.:.     |..|....:..|..||..::...|||:||    .|.
  Rat   232 EASEDAAFNKITRSLQDLQQKDIG-----VKPEFSFNIPRAKRELGQLNKCTSPQQKL----LCL 287

  Fly   299 RHIFELLKRATGGPAS--------ADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRLMSGES 355
            |.:.:|:   |..|:.        |||.|..|:::::|.......:|::::..|..:|. ...|.
  Rat   288 RKVVQLM---TQSPSQRVNLETVCADDLLSVLLYLLVKTEIPNWMANLSYIKNFRFSSS-PKDEL 348

  Fly   356 GYYFTNLCSAIAFIENLNGESLGVSSEEFEA------------LMSGQQPYSTPWESALLACESL 408
            ||..|::.:||.:|..   .||.....:.|.            |:|  |..|||     :.|...
  Rat   349 GYCLTSVEAAIEYIRQ---GSLSAQPPDAEGFGDRLFLKQRMNLLS--QMSSTP-----IDCLFK 403

  Fly   409 HLISENMKRMEML-----QKRNAL--ISSGITSFEKELIDFQREVTERVDTVIAKAPLNLLPI-- 464
            |:.|.|.|.:|.|     |.::|:  :...:.|.|    |.::.|:.|::.     |..:.|.  
  Rat   404 HIASGNQKEVERLLSQDDQDKDAMQKMCHPLCSCE----DCEKLVSGRLND-----PSVVTPFSR 459

  Fly   465 ----KTP---AFLIGQARAHLLNESEAGHYQANMLHGGSLTSQSLTAAGGLVKPAAASKESGLSL 522
                :||   |.|.|||.......|:.....|...||.:              |...:.:.|.. 
  Rat   460 DDRGQTPLHVAALCGQASLIDFLVSKGAVVNATDYHGST--------------PLHLACQKGFQ- 509

  Fly   523 KDTSMSSMGRLSPLQQNVQPADHLFASPIF---NYTAFDAVSLLEEPVPDANTDVLMLGSEFQGG 584
               |::.:  |...:.|.:..|:...:|:.   .|...|.|..|                     
  Rat   510 ---SVTLL--LLHYKANTEVQDNNGNTPLHLACTYGQEDCVKAL--------------------- 548

  Fly   585 LTNINYD-----FDLSDQSGENSTADESKLNLDE-FDPLAQKGLVAKPPPPLPETSL---LDSTT 640
               :.||     .|:.::.|:.:....::...:. .:.|.|.|........|.||.|   |:|..
  Rat   549 ---VYYDVQACRLDIGNEKGDTALHIAARWGYEGIIETLLQNGAPTAIQNRLKETPLKCALNSKI 610

  Fly   641 DSLID------------SEVPGTAVLLPSPLKPEVSNYRGFSNFDIPSIS 678
            .|.::            ||||.     |||.:...|..:|.|.....|:|
  Rat   611 LSAMEAYHLSSDRRPKPSEVPA-----PSPTRSADSISQGSSTSSFSSVS 655

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rabex-5NP_612093.1 zf-A20 17..40 CDD:460313
DUF5601 163..220 CDD:465668 9/46 (20%)
VPS9 274..373 CDD:460489 29/106 (27%)
Ankrd27NP_001258193.1 VPS9 264..363 CDD:473191 28/106 (26%)
Ank_2 <387..493 CDD:463710 31/121 (26%)
ANKRD27_zf1 429..468 CDD:439265 9/47 (19%)
ANKYR <459..616 CDD:440430 36/200 (18%)
ANK repeat 462..493 CDD:293786 9/30 (30%)
ANK repeat 495..526 CDD:293786 7/50 (14%)
ANK repeat 528..556 CDD:293786 7/51 (14%)
ANK repeat 564..595 CDD:293786 4/30 (13%)
ANKYR <725..894 CDD:440430
ANK repeat 743..774 CDD:293786
ANK repeat 776..807 CDD:293786
ANK repeat 809..840 CDD:293786
ANK repeat 842..873 CDD:293786
Blue background indicates that the domain is not in the aligned region.

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