Protein Alignment Rabex-5 and Rabgef1

DIOPT Version :10

• Sequence 1: NP_612093.1
• Gene: Rabex-5 / 38144
• FlyBaseID: FBgn0262937
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_063127563.1
• Gene: Rabgef1 / 360797
• RGDID: 1307295
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 496
• Identity: 163/496 - (32%)
• Similarity: 252/496 - (50%)
• Gaps: 58/496 - (11%)

  Fly     1 MSTAARPPSLRLGQQDLKCRSGCGFYGTPQNEGLCSMCFREKFND-KQRKLKQTGGETGPGSSSS 64
            ||..:....:.:.|.:|.|:.|||:||.|..:|.||.|:||:::. :||::::         ...
  Rat    79 MSLKSERRGIHVDQSELLCKKGCGYYGNPAWQGFCSKCWREEYHKARQRQIQE---------DWE 134

  Fly    65 VATLDRRSPQHAHLQGKVEQ--------QVRKPSDKEQDNLGTLQKKKFTAVLQKTLQAGAQKIT 121
            :|...:|..:.|....:..|        :..:....|:....|..||.|:|    :.:||::|..
  Rat   135 LAERLQREEEEAFASSQSSQGAQSLTFSKFEEKKTNEKTRKVTTVKKFFSA----SSRAGSKKAE 195

  Fly   122 QQRGHVPDPTEGQFLLQLRQLRIPDDGKRKLKLEI--------QRLDSDIRKYMNGNGGK---NI 175
            .|....|.|:..      ||..|..|...|..::.        |.:....:.::.....|   :|
  Rat   196 IQEAKAPSPSIN------RQTSIETDRVTKEFIDFLKTFHKTGQEVYKQTKMFLEAMPYKRDLSI 254

  Fly   176 NELSDLVQNAYTKVSDIVHNDPSFEIATN-----EDRDSAIDFFEKVVMTQNHKFLFSPYFTTDE 235
            .|.|:..|:.|..|::        .:.|.     |..:..:|..||.:||:.:||:|.|..|.||
  Rat   255 EEQSECTQDFYQNVAE--------RLQTRGKVPPEKVEKMMDQIEKHIMTRLYKFVFCPETTDDE 311

  Fly   236 DSDVKVQKRIRQLSWITAKHLDCSIDEVNSEARDLVYNAISELVGIDSYYSPQEKLQCTWRCCRH 300
            ..|:.:|||||.|.|:|.:.|...::|...|..|:|..||::::.:||...|::||.|..||.:|
  Rat   312 KKDLAIQKRIRALHWVTPQMLCVPVNEEIPEVSDMVVKAITDIIEMDSKRVPRDKLACITRCSKH 376

  Fly   301 IFELLKRATGGPASADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRLMSGESGYYFTNLCSA 365
            ||..:|.....|||||||||.||::|||.||.||.|||.::|||.|.||||:||.||||||||.|
  Rat   377 IFNAIKITKNEPASADDFLPTLIYIVLKGNPPRLQSNIQYITRFCNPSRLMTGEDGYYFTNLCCA 441

  Fly   366 IAFIENLNGESLGVSSEEFEALMSGQ----QPYSTPWESALLACESLHLISENMKRMEMLQKRNA 426
            :||||.|:.:||.:|.|:|:..||||    :..|..|...  ||..:..:.:|:..:..|.:|..
  Rat   442 VAFIEKLDAQSLNLSQEDFDRYMSGQTSPRKQESESWSPE--ACLGVKQMYKNLDLLSQLNERQE 504

  Fly   427 LISSGITSFEKELIDFQREVTERVDTVIAKAPLNLLPIKTP 467
            .|.:.....||:|||:...:.:.|..::.|.||.:.|...|
  Rat   505 RIMTEAKKLEKDLIDWTDGIAKEVQDIVEKYPLEIKPPNQP 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rabex-5	NP_612093.1	zf-A20	17..40	CDD:460313	12/22 (55%)
		DUF5601	163..220	CDD:465668	12/64 (19%)
		VPS9	274..373	CDD:460489	58/98 (59%)
Rabgef1	XP_063127563.1	None