Protein Alignment Rabex-5 and Rin3

DIOPT Version :10

• Sequence 1: NP_612093.1
• Gene: Rabex-5 / 38144
• FlyBaseID: FBgn0262937
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001401858.1
• Gene: Rin3 / 314397
• RGDID: 1305849
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 486
• Identity: 90/486 - (18%)
• Similarity: 170/486 - (34%)
• Gaps: 129/486 - (26%)

  Fly     8 PSLRLGQQDLKCRSGCGFYGTPQNEG-LCSMCFREKFNDKQRKLKQTGGETGPGSSSSVATLDRR 71
            |:.:.|.|.|:.::......:|:.:| |.|:      :|..........:....:||:...|:..
  Rat   502 PAGQAGMQHLQVQTSACPQSSPEFKGSLASL------SDSLGVPASAADQDSYSTSSAEEELEFS 560

  Fly    72 SPQHAHLQGKVEQQVRKPS---DKEQDNLGTLQKKKFTAVLQKTLQAGAQ------KITQQRGHV 127
            ||          ...:|||   ||.:..|..   ..||:|....|.:..:      ::.|.:|..
  Rat   561 SP----------NVKKKPSMILDKARHRLSF---ASFTSVFHAFLSSDRKLYKKVVELAQDKGSY 612

  Fly   128 PDPTEGQFLLQLRQLRIPDDGKRKLKLEIQRLDSDIRKYMNGNGGKNINELSDLVQNAYTK--VS 190
            .......:.:...::........::..||:.:.:.::.|              |:|:...|  |.
  Rat   613 FGSLVQDYKVYSLEMMTRQTSSTEMLQEIRTMMTQLKSY--------------LLQSTELKALVE 663

  Fly   191 DIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYFTTDEDSDVKVQKRIRQLSWITAKH 255
            ..:|::               :..|.:|.:..:|.:..|.......|.:::..|...|..:....
  Rat   664 PTLHSE---------------EELEAIVESALYKCVLKPLKEAINSSLLEIHSRDGSLQQLKENQ 713

  Fly   256 L------------DCSIDEVNSEARDLVYNAISELVGIDSYYSPQEKLQCTWRCCRHIFELLKRA 308
            |            ..|:.||     .::...:.:|..:...|||.:|:....:.|:.|::.:...
  Rat   714 LVILATTTTDLGVTTSVPEV-----AVMEKILQKLTNMHKAYSPGKKISILLKTCKLIYDSMALG 773

  Fly   309 T-GGPASADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRLMSGESGYYFTNLCSAIAFIENL 372
            . |.|..||||||.|::|:.::|...:..|:.::....:.: |..||..||.|....|:..|:|.
  Rat   774 NPGKPYGADDFLPVLMYVLARSNLTEMLLNVEYMMELMDPA-LQLGEGSYYLTTTYGALEHIKNY 837

  Fly   373 N----GESLGVSSEEFEALMSGQQPYSTPWESALLACESLHLISENMKRMEMLQKRNALISSGIT 433
            :    ...|.|..:                       :|:|    ..:|...|.|..|..||
  Rat   838 DKITVTRQLSVEVQ-----------------------DSIH----RWERRRTLNKARASRSS--- 872

  Fly   434 SFEKELIDF-----------QREVTERVDTV 453
                 :.||           .|.:..|.|||
  Rat   873 -----VQDFICVSYLQPEQQSRTLASRADTV 898

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rabex-5	NP_612093.1	zf-A20	17..40	CDD:460313	5/23 (22%)
		DUF5601	163..220	CDD:465668	8/58 (14%)
		VPS9	274..373	CDD:460489	28/99 (28%)
Rin3	NP_001401858.1	SH2_RIN3	52..153	CDD:198258
		PHA03247	<244..562	CDD:223021	12/65 (18%)
		VPS9	736..839	CDD:460489	28/103 (27%)
		RA_Rin3	874..961	CDD:340547	7/25 (28%)