DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rabex-5 and Vps9d1

DIOPT Version :9

Sequence 1:	NP_612093.1	Gene:	Rabex-5 / 38144	FlyBaseID:	FBgn0262937	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	XP_006255829.1	Gene:	Vps9d1 / 307923	RGDID:	1565149	Length:	648	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	85/348 - (24%)
Similarity:	131/348 - (37%)	Gaps:	94/348 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 GPGSSSSV-----ATLDRRSPQHAHLQGKVEQQVRKPSDKEQDNLGTLQKKKFTAVLQKTLQAGA 117
            ||.|:.|:     .||||.:.             ..|:......:|.|.
  Rat   357 GPPSTPSIPILHSGTLDREAD-------------GSPAGPSSPLVGALP---------------- 392

  Fly   118 QKITQQRGHVPDPTEG-----QFLLQLRQLRIPDDGKRKLKLEIQRLDSDIRKYMNGNGGKNINE 177
                    |:||....     || |.:.:.:.| ..||:..||.  |.|.::...|.     |:.
  Rat   393 --------HLPDKDSSFEDLEQF-LAMSEPQTP-GAKREPLLEC--LKSTVKDIHNA-----IDR 440

  Fly   178 LSDLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSPYFTTDEDSDVKVQ 242
            |..|...|:          .|...||.:||  .:...|:...:.....|.:.|.:.....:..|.
  Rat   441 LLSLTLLAF----------ESLNTATCKDR--CLACIEEPFFSPLWPLLLALYRSVHRTREAAVS 493

  Fly   243 KRIR-------QLSWITAKHLDCSIDEVNSEARDLVYNAISELVGIDSYYS-PQEKLQCTWRCCR 299
            :.:.       ....|..|.|.| :.|  ::|....|...::.:|:....| ||:||:|..|..|
  Rat   494 RSMELYRNALPTALGIPTKLLPC-VPE--AQASTYPYCTAAQELGLLVLESCPQKKLECIVRTLR 555

  Fly   300 HIFELLK--------RATGG---PAS---ADDFLPALIFVVLKANPVRLHSNINFVTRFTNASRL 350
            .|....:        |..||   ||:   |||.||.|.||||::...:|.|....:..||:...|
  Rat   556 VICICAEDYCRAQEARPEGGSQPPAAAIGADDLLPILSFVVLRSGLPQLVSECAALEEFTHEGYL 620

  Fly   351 MSGESGYYFTNLCSAIAFIENLN 373
            : ||.||..|:|.||::::|.|:
  Rat   621 I-GEEGYCLTSLQSALSYVELLS 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rabex-5	NP_612093.1	zf-A20	17..40	CDD:280010
Rabex-5	NP_612093.1	VPS9	274..373	CDD:280383	39/113 (35%)
Vps9d1	XP_006255829.1	VPS9	527..642	CDD:280383	40/115 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343785
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2319
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740