DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rabex-5 and rme-6

DIOPT Version :9

Sequence 1:	NP_612093.1	Gene:	Rabex-5 / 38144	FlyBaseID:	FBgn0262937	Length:	696	Species:	Drosophila melanogaster
Sequence 2:	NP_508208.2	Gene:	rme-6 / 180463	WormBaseID:	WBGene00004377	Length:	1093	Species:	Caenorhabditis elegans

Alignment Length:	218	Identity:	61/218 - (27%)
Similarity:	101/218 - (46%)	Gaps:	25/218 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 KYMNGNGGKNINELSDLVQNAYTKVSDIVHNDPSFEIATNEDRDSAIDFFEKVVMTQNHKFLFSP 229
            ||:...     :|.::.::|..|.:.|.:..:..:..||:.....|:...|:.|:...:...|.|
Worm   890 KYLRAQ-----DERAEFLKNLLTFLRDRLMQNVDWNFATDTMMSRAMTTIERYVIFAVYDNAFYP 949

  Fly   230 YFTTDEDSDVKVQKRIRQLSWITA---------KHLDCSIDEVNSEARDLVYNAISELVGIDSYY 285
            ....|...|..::..|.::|.:..         :||.......:::|         ||..:|.|.
Worm   950 NRDADHHRDKLLRGTIAKVSDVVTPVNDFLKIPEHLHGEAPWPSAQA---------ELSMLDIYV 1005

  Fly   286 SPQEKLQCTWRCCRHIFELLKRAT-GGPASADDFLPALIFVVLKANPVRLHSNINFVTRFTNASR 349
            :.|:||.|..|||..|..|:..:: ...|||||..|.|:||::||||..|.||:.||..|. ..|
Worm  1006 TAQDKLNCVVRCCDVINNLVALSSKNAVASADDLTPVLVFVIIKANPRALLSNVQFVETFA-GDR 1069

  Fly   350 LMSGESGYYFTNLCSAIAFIENL 372
            :.||...||:.|..||:.:|:.:
Worm  1070 IESGRDAYYWVNFKSAVEYIKTI 1092

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rabex-5	NP_612093.1	zf-A20	17..40	CDD:280010
Rabex-5	NP_612093.1	VPS9	274..373	CDD:280383	41/100 (41%)
rme-6	NP_508208.2	RasGAP_RAP6	93..437	CDD:213331
rme-6	NP_508208.2	VPS9	990..1093	CDD:128469	42/113 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D944088at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920